Garcia ML - Search Results

1

ProTx-II, a selective inhibitor of NaV1.7 sodium channels, blocks action potential propagation in nociceptors.

Schmalhofer WA, Calhoun J, Burrows R, Bailey T, Kohler MG, Weinglass AB, Kaczorowski GJ, Garcia ML, Koltzenburg M, Priest BT. Schmalhofer WA, et al. Among authors: garcia ml. Mol Pharmacol. 2008 Nov;74(5):1476-84. doi: 10.1124/mol.108.047670. Epub 2008 Aug 26. Mol Pharmacol. 2008. PMID: 18728100

2

Functional assay of voltage-gated sodium channels using membrane potential-sensitive dyes.

Felix JP, Williams BS, Priest BT, Brochu RM, Dick IE, Warren VA, Yan L, Slaughter RS, Kaczorowski GJ, Smith MM, Garcia ML. Felix JP, et al. Among authors: garcia ml. Assay Drug Dev Technol. 2004 Jun;2(3):260-8. doi: 10.1089/1540658041410696. Assay Drug Dev Technol. 2004. PMID: 15285907

3

Stichodactyla helianthus peptide, a pharmacological tool for studying Kv3.2 channels.

Yan L, Herrington J, Goldberg E, Dulski PM, Bugianesi RM, Slaughter RS, Banerjee P, Brochu RM, Priest BT, Kaczorowski GJ, Rudy B, Garcia ML. Yan L, et al. Among authors: garcia ml. Mol Pharmacol. 2005 May;67(5):1513-21. doi: 10.1124/mol.105.011064. Epub 2005 Feb 11. Mol Pharmacol. 2005. PMID: 15709110

4

Potassium channels as targets for therapeutic intervention.

Garcia ML, Kaczorowski GJ. Garcia ML, et al. Sci STKE. 2005 Sep 20;2005(302):pe46. doi: 10.1126/stke.stke.3022005pe46. Sci STKE. 2005. PMID: 16174819 Review.

5

A high-capacity membrane potential FRET-based assay for NaV1.8 channels.

Liu CJ, Priest BT, Bugianesi RM, Dulski PM, Felix JP, Dick IE, Brochu RM, Knaus HG, Middleton RE, Kaczorowski GJ, Slaughter RS, Garcia ML, Köhler MG. Liu CJ, et al. Among authors: garcia ml. Assay Drug Dev Technol. 2006 Feb;4(1):37-48. doi: 10.1089/adt.2006.4.37. Assay Drug Dev Technol. 2006. PMID: 16506887

6

Ion channel modulators: new targets and new indications for old targets.

Priest B, Kaczorowski GJ, Garcia ML. Priest B, et al. Among authors: garcia ml. Curr Opin Drug Discov Devel. 2006 Sep;9(5):587-94. Curr Opin Drug Discov Devel. 2006. PMID: 17002219 Review.

7

Characterization of a new class of potent inhibitors of the voltage-gated sodium channel Nav1.7.

Williams BS, Felix JP, Priest BT, Brochu RM, Dai K, Hoyt SB, London C, Tang YS, Duffy JL, Parsons WH, Kaczorowski GJ, Garcia ML. Williams BS, et al. Among authors: garcia ml. Biochemistry. 2007 Dec 18;46(50):14693-703. doi: 10.1021/bi7018207. Epub 2007 Nov 21. Biochemistry. 2007. PMID: 18027973

8

Madin-Darby canine kidney II cells: a pharmacologically validated system for NPC1L1-mediated cholesterol uptake.

Weinglass AB, Köhler MG, Nketiah EO, Liu J, Schmalhofer W, Thomas A, Williams B, Beers L, Smith L, Hafey M, Bleasby K, Leone J, Tang YS, Braun M, Ujjainwalla F, McCann ME, Kaczorowski GJ, Garcia ML. Weinglass AB, et al. Among authors: garcia ml. Mol Pharmacol. 2008 Apr;73(4):1072-84. doi: 10.1124/mol.107.043844. Epub 2008 Jan 10. Mol Pharmacol. 2008. PMID: 18187582

9

Ion channels as drug targets: the next GPCRs.

Kaczorowski GJ, McManus OB, Priest BT, Garcia ML. Kaczorowski GJ, et al. Among authors: garcia ml. J Gen Physiol. 2008 May;131(5):399-405. doi: 10.1085/jgp.200709946. Epub 2008 Apr 14. J Gen Physiol. 2008. PMID: 18411331 Free PMC article. No abstract available.

10

A KV2.1 gating modifier binding assay suitable for high throughput screening.

Schmalhofer WA, Ratliff KS, Weinglass A, Kaczorowski GJ, Garcia ML, Herrington J. Schmalhofer WA, et al. Among authors: garcia ml. Channels (Austin). 2009 Nov;3(6):437-47. doi: 10.4161/chan.3.6.10201. Channels (Austin). 2009. PMID: 21150283 Free article.

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