Teruya-Feldstein J - Search Results

1

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer.

Carracedo A, Ma L, Teruya-Feldstein J, Rojo F, Salmena L, Alimonti A, Egia A, Sasaki AT, Thomas G, Kozma SC, Papa A, Nardella C, Cantley LC, Baselga J, Pandolfi PP. Carracedo A, et al. J Clin Invest. 2008 Sep;118(9):3065-74. doi: 10.1172/JCI34739. J Clin Invest. 2008. PMID: 18725988 Free PMC article.

2

PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR.

Bernardi R, Guernah I, Jin D, Grisendi S, Alimonti A, Teruya-Feldstein J, Cordon-Cardo C, Simon MC, Rafii S, Pandolfi PP. Bernardi R, et al. Nature. 2006 Aug 17;442(7104):779-85. doi: 10.1038/nature05029. Nature. 2006. PMID: 16915281

3

Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer.

Ma L, Teruya-Feldstein J, Bonner P, Bernardi R, Franz DN, Witte D, Cordon-Cardo C, Pandolfi PP. Ma L, et al. Cancer Res. 2007 Aug 1;67(15):7106-12. doi: 10.1158/0008-5472.CAN-06-4798. Cancer Res. 2007. PMID: 17671177

4

The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network.

Song MS, Salmena L, Carracedo A, Egia A, Lo-Coco F, Teruya-Feldstein J, Pandolfi PP. Song MS, et al. Nature. 2008 Oct 9;455(7214):813-7. doi: 10.1038/nature07290. Epub 2008 Aug 20. Nature. 2008. PMID: 18716620 Free PMC article.

5

Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling.

Gewinner C, Wang ZC, Richardson A, Teruya-Feldstein J, Etemadmoghadam D, Bowtell D, Barretina J, Lin WM, Rameh L, Salmena L, Pandolfi PP, Cantley LC. Gewinner C, et al. Cancer Cell. 2009 Aug 4;16(2):115-25. doi: 10.1016/j.ccr.2009.06.006. Cancer Cell. 2009. PMID: 19647222 Free PMC article.

6

Differential p53-independent outcomes of p19(Arf) loss in oncogenesis.

Chen Z, Carracedo A, Lin HK, Koutcher JA, Behrendt N, Egia A, Alimonti A, Carver BS, Gerald W, Teruya-Feldstein J, Loda M, Pandolfi PP. Chen Z, et al. Sci Signal. 2009 Aug 18;2(84):ra44. doi: 10.1126/scisignal.2000053. Sci Signal. 2009. PMID: 19690330 Free PMC article.

7

Pml represses tumour progression through inhibition of mTOR.

Bernardi R, Papa A, Egia A, Coltella N, Teruya-Feldstein J, Signoretti S, Pandolfi PP. Bernardi R, et al. EMBO Mol Med. 2011 May;3(5):249-57. doi: 10.1002/emmm.201100130. Epub 2011 Mar 8. EMBO Mol Med. 2011. PMID: 21387562 Free PMC article.

8

PML targeting eradicates quiescent leukaemia-initiating cells.

Ito K, Bernardi R, Morotti A, Matsuoka S, Saglio G, Ikeda Y, Rosenblatt J, Avigan DE, Teruya-Feldstein J, Pandolfi PP. Ito K, et al. Nature. 2008 Jun 19;453(7198):1072-8. doi: 10.1038/nature07016. Epub 2008 May 11. Nature. 2008. PMID: 18469801 Free PMC article.

9

Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.

Lin HK, Chen Z, Wang G, Nardella C, Lee SW, Chan CH, Yang WL, Wang J, Egia A, Nakayama KI, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP. Lin HK, et al. Nature. 2010 Mar 18;464(7287):374-9. doi: 10.1038/nature08815. Nature. 2010. PMID: 20237562 Free PMC article.

10

Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression.

Ma L, Teruya-Feldstein J, Behrendt N, Chen Z, Noda T, Hino O, Cordon-Cardo C, Pandolfi PP. Ma L, et al. Genes Dev. 2005 Aug 1;19(15):1779-86. doi: 10.1101/gad.1314405. Epub 2005 Jul 18. Genes Dev. 2005. PMID: 16027168 Free PMC article.

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