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Epoxyeicosatrienoic acids and the soluble epoxide hydrolase are determinants of pulmonary artery pressure and the acute hypoxic pulmonary vasoconstrictor response.
Keserü B, Barbosa-Sicard E, Popp R, Fisslthaler B, Dietrich A, Gudermann T, Hammock BD, Falck JR, Weissmann N, Busse R, Fleming I. Keserü B, et al. Among authors: gudermann t. FASEB J. 2008 Dec;22(12):4306-15. doi: 10.1096/fj.08-112821. Epub 2008 Aug 25. FASEB J. 2008. PMID: 18725458 Free PMC article.
Increased vascular smooth muscle contractility in TRPC6-/- mice.
Dietrich A, Mederos Y Schnitzler M, Gollasch M, Gross V, Storch U, Dubrovska G, Obst M, Yildirim E, Salanova B, Kalwa H, Essin K, Pinkenburg O, Luft FC, Gudermann T, Birnbaumer L. Dietrich A, et al. Among authors: gudermann t. Mol Cell Biol. 2005 Aug;25(16):6980-9. doi: 10.1128/MCB.25.16.6980-6989.2005. Mol Cell Biol. 2005. PMID: 16055711 Free PMC article.
Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange.
Weissmann N, Dietrich A, Fuchs B, Kalwa H, Ay M, Dumitrascu R, Olschewski A, Storch U, Mederos y Schnitzler M, Ghofrani HA, Schermuly RT, Pinkenburg O, Seeger W, Grimminger F, Gudermann T. Weissmann N, et al. Among authors: gudermann t. Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19093-8. doi: 10.1073/pnas.0606728103. Epub 2006 Dec 1. Proc Natl Acad Sci U S A. 2006. PMID: 17142322 Free PMC article.
Reduced rather than enhanced cholinergic airway constriction in mice with ablation of the large conductance Ca2+-activated K+ channel.
Sausbier M, Zhou XB, Beier C, Sausbier U, Wolpers D, Maget S, Martin C, Dietrich A, Ressmeyer AR, Renz H, Schlossmann J, Hofmann F, Neuhuber W, Gudermann T, Uhlig S, Korth M, Ruth P. Sausbier M, et al. Among authors: gudermann t. FASEB J. 2007 Mar;21(3):812-22. doi: 10.1096/fj.06-7167com. Epub 2006 Dec 28. FASEB J. 2007. PMID: 17197382
325 results