Zakkar M - Search Results

1

Increased endothelial mitogen-activated protein kinase phosphatase-1 expression suppresses proinflammatory activation at sites that are resistant to atherosclerosis.

Zakkar M, Chaudhury H, Sandvik G, Enesa K, Luong le A, Cuhlmann S, Mason JC, Krams R, Clark AR, Haskard DO, Evans PC. Zakkar M, et al. Circ Res. 2008 Sep 26;103(7):726-32. doi: 10.1161/CIRCRESAHA.108.183913. Epub 2008 Aug 21. Circ Res. 2008. PMID: 18723442

2

Laminar shear stress acts as a switch to regulate divergent functions of NF-kappaB in endothelial cells.

Partridge J, Carlsen H, Enesa K, Chaudhury H, Zakkar M, Luong L, Kinderlerer A, Johns M, Blomhoff R, Mason JC, Haskard DO, Evans PC. Partridge J, et al. Among authors: zakkar m. FASEB J. 2007 Nov;21(13):3553-61. doi: 10.1096/fj.06-8059com. Epub 2007 Jun 8. FASEB J. 2007. PMID: 17557931

3

NF-kappaB suppression by the deubiquitinating enzyme Cezanne: a novel negative feedback loop in pro-inflammatory signaling.

Enesa K, Zakkar M, Chaudhury H, Luong le A, Rawlinson L, Mason JC, Haskard DO, Dean JL, Evans PC. Enesa K, et al. Among authors: zakkar m. J Biol Chem. 2008 Mar 14;283(11):7036-45. doi: 10.1074/jbc.M708690200. Epub 2008 Jan 4. J Biol Chem. 2008. PMID: 18178551 Free article.

4

The A20 gene protects kidneys from ischaemia/reperfusion injury by suppressing pro-inflammatory activation.

Lutz J, Luong le A, Strobl M, Deng M, Huang H, Anton M, Zakkar M, Enesa K, Chaudhury H, Haskard DO, Baumann M, Boyle J, Harten S, Maxwell PH, Pusey C, Heemann U, Evans PC. Lutz J, et al. Among authors: zakkar m. J Mol Med (Berl). 2008 Dec;86(12):1329-39. doi: 10.1007/s00109-008-0405-4. Epub 2008 Sep 24. J Mol Med (Berl). 2008. PMID: 18813897

5

Induction of the cytoprotective enzyme heme oxygenase-1 by statins is enhanced in vascular endothelium exposed to laminar shear stress and impaired by disturbed flow.

Ali F, Zakkar M, Karu K, Lidington EA, Hamdulay SS, Boyle JJ, Zloh M, Bauer A, Haskard DO, Evans PC, Mason JC. Ali F, et al. Among authors: zakkar m. J Biol Chem. 2009 Jul 10;284(28):18882-92. doi: 10.1074/jbc.M109.009886. Epub 2009 May 19. J Biol Chem. 2009. PMID: 19457866 Free PMC article.

6

Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state.

Zakkar M, Van der Heiden K, Luong le A, Chaudhury H, Cuhlmann S, Hamdulay SS, Krams R, Edirisinghe I, Rahman I, Carlsen H, Haskard DO, Mason JC, Evans PC. Zakkar M, et al. Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1851-7. doi: 10.1161/ATVBAHA.109.193375. Epub 2009 Sep 3. Arterioscler Thromb Vasc Biol. 2009. PMID: 19729611

7

Perfusion of veins at arterial pressure increases the expression of KLF5 and cell cycle genes in smooth muscle cells.

Amirak E, Zakkar M, Evans PC, Kemp PR. Amirak E, et al. Among authors: zakkar m. Biochem Biophys Res Commun. 2010 Jan 1;391(1):818-23. doi: 10.1016/j.bbrc.2009.11.145. Epub 2009 Dec 2. Biochem Biophys Res Commun. 2010. PMID: 19958749 Free PMC article.

8

c-Jun N-terminal kinase primes endothelial cells at atheroprone sites for apoptosis.

Chaudhury H, Zakkar M, Boyle J, Cuhlmann S, van der Heiden K, Luong le A, Davis J, Platt A, Mason JC, Krams R, Haskard DO, Clark AR, Evans PC. Chaudhury H, et al. Among authors: zakkar m. Arterioscler Thromb Vasc Biol. 2010 Mar;30(3):546-53. doi: 10.1161/ATVBAHA.109.201368. Epub 2010 Jan 7. Arterioscler Thromb Vasc Biol. 2010. PMID: 20056910 Free article.

9

Role of nuclear factor kappaB in cardiovascular health and disease.

Van der Heiden K, Cuhlmann S, Luong le A, Zakkar M, Evans PC. Van der Heiden K, et al. Among authors: zakkar m. Clin Sci (Lond). 2010 Feb 23;118(10):593-605. doi: 10.1042/CS20090557. Clin Sci (Lond). 2010. PMID: 20175746 Review.

10

Smooth muscle cells in porcine vein graft intimal hyperplasia are derived from the local vessel wall.

Jevon M, Ansari TI, Finch J, Zakkar M, Evans PC, Shurey S, Sibbons PD, Hornick P, Haskard DO, Dorling A. Jevon M, et al. Among authors: zakkar m. Cardiovasc Pathol. 2011 May-Jun;20(3):e91-4. doi: 10.1016/j.carpath.2010.04.003. Epub 2010 Jun 7. Cardiovasc Pathol. 2011. PMID: 20537564

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