Gould MK - Search Results

1

Propidium iodide-based methods for monitoring drug action in the kinetoplastidae: comparison with the Alamar Blue assay.

Gould MK, Vu XL, Seebeck T, de Koning HP. Gould MK, et al. Anal Biochem. 2008 Nov 15;382(2):87-93. doi: 10.1016/j.ab.2008.07.036. Epub 2008 Aug 3. Anal Biochem. 2008. PMID: 18722997

2

Molecular interactions underlying the unusually high adenosine affinity of a novel Trypanosoma brucei nucleoside transporter.

Al-Salabi MI, Wallace LJ, Lüscher A, Mäser P, Candlish D, Rodenko B, Gould MK, Jabeen I, Ajith SN, de Koning HP. Al-Salabi MI, et al. Among authors: gould mk. Mol Pharmacol. 2007 Mar;71(3):921-9. doi: 10.1124/mol.106.031559. Epub 2006 Dec 21. Mol Pharmacol. 2007. PMID: 17185380

3

Loss of the high-affinity pentamidine transporter is responsible for high levels of cross-resistance between arsenical and diamidine drugs in African trypanosomes.

Bridges DJ, Gould MK, Nerima B, Mäser P, Burchmore RJ, de Koning HP. Bridges DJ, et al. Among authors: gould mk. Mol Pharmacol. 2007 Apr;71(4):1098-108. doi: 10.1124/mol.106.031351. Epub 2007 Jan 18. Mol Pharmacol. 2007. PMID: 17234896

4

2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities.

Rodenko B, van der Burg AM, Wanner MJ, Kaiser M, Brun R, Gould M, de Koning HP, Koomen GJ. Rodenko B, et al. Antimicrob Agents Chemother. 2007 Nov;51(11):3796-802. doi: 10.1128/AAC.00425-07. Epub 2007 Aug 13. Antimicrob Agents Chemother. 2007. PMID: 17698622 Free PMC article.

5

Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species.

Changtam C, de Koning HP, Ibrahim H, Sajid MS, Gould MK, Suksamrarn A. Changtam C, et al. Among authors: gould mk. Eur J Med Chem. 2010 Mar;45(3):941-56. doi: 10.1016/j.ejmech.2009.11.035. Epub 2009 Nov 24. Eur J Med Chem. 2010. PMID: 20004045

6

Cyclic-nucleotide signalling in protozoa.

Gould MK, de Koning HP. Gould MK, et al. FEMS Microbiol Rev. 2011 May;35(3):515-41. doi: 10.1111/j.1574-6976.2010.00262.x. Epub 2011 Jan 26. FEMS Microbiol Rev. 2011. PMID: 21223322 Free article. Review.

7

Pharmacological validation of Trypanosoma brucei phosphodiesterases as novel drug targets.

de Koning HP, Gould MK, Sterk GJ, Tenor H, Kunz S, Luginbuehl E, Seebeck T. de Koning HP, et al. Among authors: gould mk. J Infect Dis. 2012 Jul 15;206(2):229-37. doi: 10.1093/infdis/jir857. Epub 2012 Jan 30. J Infect Dis. 2012. PMID: 22291195 Free PMC article.

8

Cyclic AMP effectors in African trypanosomes revealed by genome-scale RNA interference library screening for resistance to the phosphodiesterase inhibitor CpdA.

Gould MK, Bachmaier S, Ali JA, Alsford S, Tagoe DN, Munday JC, Schnaufer AC, Horn D, Boshart M, de Koning HP. Gould MK, et al. Antimicrob Agents Chemother. 2013 Oct;57(10):4882-93. doi: 10.1128/AAC.00508-13. Epub 2013 Jul 22. Antimicrob Agents Chemother. 2013. PMID: 23877697 Free PMC article.

9

Reduced Mitochondrial Membrane Potential Is a Late Adaptation of Trypanosoma brucei brucei to Isometamidium Preceded by Mutations in the γ Subunit of the F1Fo-ATPase.

Eze AA, Gould MK, Munday JC, Tagoe DN, Stelmanis V, Schnaufer A, De Koning HP. Eze AA, et al. Among authors: gould mk. PLoS Negl Trop Dis. 2016 Aug 12;10(8):e0004791. doi: 10.1371/journal.pntd.0004791. eCollection 2016 Aug. PLoS Negl Trop Dis. 2016. PMID: 27518185 Free PMC article.

10

Novel kinetoplastid-specific cAMP binding proteins identified by RNAi screening for cAMP resistance in Trypanosoma brucei.

Bachmaier S, Gould MK, Polatoglou E, Omelianczyk R, Brennand AE, Aloraini MA, Munday JC, Horn D, Boshart M, de Koning HP. Bachmaier S, et al. Among authors: gould mk. Front Cell Infect Microbiol. 2023 Jul 5;13:1204707. doi: 10.3389/fcimb.2023.1204707. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37475965 Free PMC article.

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