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Preventing growth of brain tumors by creating a zone of resistance.
Maguire CA, Meijer DH, LeRoy SG, Tierney LA, Broekman ML, Costa FF, Breakefield XO, Stemmer-Rachamimov A, Sena-Esteves M. Maguire CA, et al. Among authors: broekman ml. Mol Ther. 2008 Oct;16(10):1695-702. doi: 10.1038/mt.2008.168. Epub 2008 Aug 19. Mol Ther. 2008. PMID: 18714312 Free PMC article.
Glioma EVs Contribute to Immune Privilege in the Brain.
Abels ER, Broekman MLD, Breakefield XO, Maas SLN. Abels ER, et al. Trends Cancer. 2019 Jul;5(7):393-396. doi: 10.1016/j.trecan.2019.05.006. Epub 2019 Jun 4. Trends Cancer. 2019. PMID: 31311653 Free PMC article. Review.
Glioblastomas exploit truncated O-linked glycans for local and distant immune modulation via the macrophage galactose-type lectin.
Dusoswa SA, Verhoeff J, Abels E, Méndez-Huergo SP, Croci DO, Kuijper LH, de Miguel E, Wouters VMCJ, Best MG, Rodriguez E, Cornelissen LAM, van Vliet SJ, Wesseling P, Breakefield XO, Noske DP, Würdinger T, Broekman MLD, Rabinovich GA, van Kooyk Y, Garcia-Vallejo JJ. Dusoswa SA, et al. Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3693-3703. doi: 10.1073/pnas.1907921117. Epub 2020 Feb 4. Proc Natl Acad Sci U S A. 2020. PMID: 32019882 Free PMC article.
Glioblastoma hijacks microglial gene expression to support tumor growth.
Maas SLN, Abels ER, Van De Haar LL, Zhang X, Morsett L, Sil S, Guedes J, Sen P, Prabhakar S, Hickman SE, Lai CP, Ting DT, Breakefield XO, Broekman MLD, El Khoury J. Maas SLN, et al. J Neuroinflammation. 2020 Apr 16;17(1):120. doi: 10.1186/s12974-020-01797-2. J Neuroinflammation. 2020. PMID: 32299465 Free PMC article.
220 results