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Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression.
Rhodes J, Amsterdam A, Sanda T, Moreau LA, McKenna K, Heinrichs S, Ganem NJ, Ho KW, Neuberg DS, Johnston A, Ahn Y, Kutok JL, Hromas R, Wray J, Lee C, Murphy C, Radtke I, Downing JR, Fleming MD, MacConaill LE, Amatruda JF, Gutierrez A, Galinsky I, Stone RM, Ross EA, Pellman DS, Kanki JP, Look AT. Rhodes J, et al. Among authors: neuberg ds. Mol Cell Biol. 2009 Nov;29(21):5911-22. doi: 10.1128/MCB.00558-09. Epub 2009 Aug 24. Mol Cell Biol. 2009. PMID: 19704007 Free PMC article.
The TCA cycle transferase DLST is important for MYC-mediated leukemogenesis.
Anderson NM, Li D, Peng HL, Laroche FJ, Mansour MR, Gjini E, Aioub M, Helman DJ, Roderick JE, Cheng T, Harrold I, Samaha Y, Meng L, Amsterdam A, Neuberg DS, Denton TT, Sanda T, Kelliher MA, Singh A, Look AT, Feng H. Anderson NM, et al. Among authors: neuberg ds. Leukemia. 2016 Jun;30(6):1365-74. doi: 10.1038/leu.2016.26. Epub 2016 Feb 15. Leukemia. 2016. PMID: 26876595 Free PMC article.
Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia.
Reynolds C, Roderick JE, LaBelle JL, Bird G, Mathieu R, Bodaar K, Colon D, Pyati U, Stevenson KE, Qi J, Harris M, Silverman LB, Sallan SE, Bradner JE, Neuberg DS, Look AT, Walensky LD, Kelliher MA, Gutierrez A. Reynolds C, et al. Among authors: neuberg ds. Leukemia. 2014 Sep;28(9):1819-27. doi: 10.1038/leu.2014.78. Epub 2014 Feb 20. Leukemia. 2014. PMID: 24552990 Free PMC article.
tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors.
Berghmans S, Murphey RD, Wienholds E, Neuberg D, Kutok JL, Fletcher CD, Morris JP, Liu TX, Schulte-Merker S, Kanki JP, Plasterk R, Zon LI, Look AT. Berghmans S, et al. Among authors: neuberg d. Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):407-12. doi: 10.1073/pnas.0406252102. Epub 2005 Jan 3. Proc Natl Acad Sci U S A. 2005. PMID: 15630097 Free PMC article.
A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility.
Shepard JL, Amatruda JF, Stern HM, Subramanian A, Finkelstein D, Ziai J, Finley KR, Pfaff KL, Hersey C, Zhou Y, Barut B, Freedman M, Lee C, Spitsbergen J, Neuberg D, Weber G, Golub TR, Glickman JN, Kutok JL, Aster JC, Zon LI. Shepard JL, et al. Among authors: neuberg d. Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13194-9. doi: 10.1073/pnas.0506583102. Epub 2005 Sep 6. Proc Natl Acad Sci U S A. 2005. PMID: 16150706 Free PMC article.
DHODH modulates transcriptional elongation in the neural crest and melanoma.
White RM, Cech J, Ratanasirintrawoot S, Lin CY, Rahl PB, Burke CJ, Langdon E, Tomlinson ML, Mosher J, Kaufman C, Chen F, Long HK, Kramer M, Datta S, Neuberg D, Granter S, Young RA, Morrison S, Wheeler GN, Zon LI. White RM, et al. Among authors: neuberg d. Nature. 2011 Mar 24;471(7339):518-22. doi: 10.1038/nature09882. Nature. 2011. PMID: 21430780 Free PMC article.
685 results