Pike LJ - Search Results

1

Correlating EGFR expression with receptor-binding properties and internalization of 64Cu-DOTA-cetuximab in 5 cervical cancer cell lines.

Eiblmaier M, Meyer LA, Watson MA, Fracasso PM, Pike LJ, Anderson CJ. Eiblmaier M, et al. Among authors: pike lj. J Nucl Med. 2008 Sep;49(9):1472-9. doi: 10.2967/jnumed.108.052316. Epub 2008 Aug 14. J Nucl Med. 2008. PMID: 18703609 Free PMC article.

2

Targeting the dimerization of epidermal growth factor receptors with small-molecule inhibitors.

Yang RY, Yang KS, Pike LJ, Marshall GR. Yang RY, et al. Among authors: pike lj. Chem Biol Drug Des. 2010 Jul;76(1):1-9. doi: 10.1111/j.1747-0285.2010.00986.x. Epub 2010 May 4. Chem Biol Drug Des. 2010. PMID: 20456371 Free PMC article.

3

Quantitation of the effect of ErbB2 on epidermal growth factor receptor binding and dimerization.

Li Y, Macdonald-Obermann J, Westfall C, Piwnica-Worms D, Pike LJ. Li Y, et al. Among authors: pike lj. J Biol Chem. 2012 Sep 7;287(37):31116-25. doi: 10.1074/jbc.M112.373647. Epub 2012 Jul 20. J Biol Chem. 2012. PMID: 22822073 Free PMC article.

4

Different epidermal growth factor (EGF) receptor ligands show distinct kinetics and biased or partial agonism for homodimer and heterodimer formation.

Macdonald-Obermann JL, Pike LJ. Macdonald-Obermann JL, et al. Among authors: pike lj. J Biol Chem. 2014 Sep 19;289(38):26178-26188. doi: 10.1074/jbc.M114.586826. Epub 2014 Aug 1. J Biol Chem. 2014. PMID: 25086039 Free PMC article.

5

Cell-cycle-dependent modulation of EGF-receptor-mediated signaling.

Newberry EP, Pike LJ. Newberry EP, et al. Among authors: pike lj. Biochem Biophys Res Commun. 1995 Mar 8;208(1):253-9. doi: 10.1006/bbrc.1995.1331. Biochem Biophys Res Commun. 1995. PMID: 7887936

6

The multiple endocrine neoplasia type 2B point mutation alters long-term regulation and enhances the transforming capacity of the epidermal growth factor receptor.

Pandit SD, Donis-Keller H, Iwamoto T, Tomich JM, Pike LJ. Pandit SD, et al. Among authors: pike lj. J Biol Chem. 1996 Mar 8;271(10):5850-8. doi: 10.1074/jbc.271.10.5850. J Biol Chem. 1996. PMID: 8621456 Free article.

7

Functional characterization of an epidermal growth factor receptor/RET chimera.

Pandit SD, O'Hare T, Donis-Keller H, Pike LJ. Pandit SD, et al. Among authors: pike lj. J Biol Chem. 1997 Jan 24;272(4):2199-206. doi: 10.1074/jbc.272.4.2199. J Biol Chem. 1997. PMID: 8999923 Free article.

8

Cholesterol depletion results in site-specific increases in epidermal growth factor receptor phosphorylation due to membrane level effects. Studies with cholesterol enantiomers.

Westover EJ, Covey DF, Brockman HL, Brown RE, Pike LJ. Westover EJ, et al. Among authors: pike lj. J Biol Chem. 2003 Dec 19;278(51):51125-33. doi: 10.1074/jbc.M304332200. Epub 2003 Oct 6. J Biol Chem. 2003. PMID: 14530278 Free PMC article.

9

Palmitoylation of the EGF receptor impairs signal transduction and abolishes high-affinity ligand binding.

Macdonald-Obermann JL, Pike LJ. Macdonald-Obermann JL, et al. Among authors: pike lj. Biochemistry. 2009 Mar 24;48(11):2505-13. doi: 10.1021/bi802249x. Biochemistry. 2009. PMID: 19196031 Free PMC article.

10

The intracellular juxtamembrane domain of the epidermal growth factor (EGF) receptor is responsible for the allosteric regulation of EGF binding.

Macdonald-Obermann JL, Pike LJ. Macdonald-Obermann JL, et al. Among authors: pike lj. J Biol Chem. 2009 May 15;284(20):13570-13576. doi: 10.1074/jbc.M109.001487. Epub 2009 Mar 31. J Biol Chem. 2009. PMID: 19336395 Free PMC article.

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