Wouters J - Search Results

1

Crystal structure of type 2 isopentenyl diphosphate isomerase from Thermus thermophilus in complex with inorganic pyrophosphate.

de Ruyck J, Pouyez J, Rothman SC, Poulter D, Wouters J. de Ruyck J, et al. Among authors: wouters j. Biochemistry. 2008 Sep 2;47(35):9051-3. doi: 10.1021/bi801159x. Epub 2008 Aug 12. Biochemistry. 2008. PMID: 18693754 Free PMC article.

2

Catalytic mechanism of Escherichia coli isopentenyl diphosphate isomerase involves Cys-67, Glu-116, and Tyr-104 as suggested by crystal structures of complexes with transition state analogues and irreversible inhibitors.

Wouters J, Oudjama Y, Barkley SJ, Tricot C, Stalon V, Droogmans L, Poulter CD. Wouters J, et al. J Biol Chem. 2003 Apr 4;278(14):11903-8. doi: 10.1074/jbc.M212823200. Epub 2003 Jan 22. J Biol Chem. 2003. PMID: 12540835 Free article.

3

Crystal structure of the C67A mutant of isopentenyl diphosphate isomerase complexed with a mechanism-based irreversible inhibitor.

Wouters J, Oudjama Y, Stalon V, Droogmans L, Poulter CD. Wouters J, et al. Proteins. 2004 Feb 1;54(2):216-21. doi: 10.1002/prot.10573. Proteins. 2004. PMID: 14696183

4

A crystallographic investigation of phosphoantigen binding to isopentenyl pyrophosphate/dimethylallyl pyrophosphate isomerase.

Wouters J, Yin F, Song Y, Zhang Y, Oudjama Y, Stalon V, Droogmans L, Morita CT, Oldfield E. Wouters J, et al. J Am Chem Soc. 2005 Jan 19;127(2):536-7. doi: 10.1021/ja040207i. J Am Chem Soc. 2005. PMID: 15643873

5

Structure of Thermus thermophilus type 2 isopentenyl diphosphate isomerase inferred from crystallography and molecular dynamics.

de Ruyck J, Rothman SC, Poulter CD, Wouters J. de Ruyck J, et al. Among authors: wouters j. Biochem Biophys Res Commun. 2005 Dec 23;338(3):1515-8. doi: 10.1016/j.bbrc.2005.10.114. Epub 2005 Oct 27. Biochem Biophys Res Commun. 2005. PMID: 16269131

6

3,6-disubstituted coumarins as mechanism-based inhibitors of thrombin and factor Xa.

Frédérick R, Robert S, Charlier C, de Ruyck J, Wouters J, Pirotte B, Masereel B, Pochet L. Frédérick R, et al. Among authors: wouters j. J Med Chem. 2005 Dec 1;48(24):7592-603. doi: 10.1021/jm050448g. J Med Chem. 2005. PMID: 16302799

7

Isopentenyl diphosphate isomerase. Mechanism-based inhibition by diene analogues of isopentenyl diphosphate and dimethylallyl diphosphate.

Wu Z, Wouters J, Poulter CD. Wu Z, et al. Among authors: wouters j. J Am Chem Soc. 2005 Dec 14;127(49):17433-8. doi: 10.1021/ja056187h. J Am Chem Soc. 2005. PMID: 16332094 Free PMC article.

8

Structural role for Tyr-104 in Escherichia coli isopentenyl-diphosphate isomerase: site-directed mutagenesis, enzymology, and protein crystallography.

de Ruyck J, Durisotti V, Oudjama Y, Wouters J. de Ruyck J, et al. Among authors: wouters j. J Biol Chem. 2006 Jun 30;281(26):17864-9. doi: 10.1074/jbc.M601851200. Epub 2006 Apr 15. J Biol Chem. 2006. PMID: 16617181 Free article.

9

Overexpression, physicochemical characterization, and modeling of a hyperthermophilic pyrococcus furiosus type 2 IPP isomerase.

Dutoit R, de Ruyck J, Durisotti V, Legrain C, Jacobs E, Wouters J. Dutoit R, et al. Among authors: wouters j. Proteins. 2008 Jun;71(4):1699-707. doi: 10.1002/prot.21863. Proteins. 2008. PMID: 18076031

10

Monoclinic form of isopentenyl diphosphate isomerase: a case of polymorphism in biomolecular crystals.

de Ruyck J, Oudjama Y, Wouters J. de Ruyck J, et al. Among authors: wouters j. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Apr 1;64(Pt 4):239-42. doi: 10.1107/S174430910800568X. Epub 2008 Mar 21. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18391416 Free PMC article.

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