Mistry P - Search Results

1

Effect of phenazine compounds XR11576 and XR5944 on DNA topoisomerases.

Jobson AG, Willmore E, Tilby MJ, Mistry P, Charlton P, Austin CA. Jobson AG, et al. Among authors: mistry p. Cancer Chemother Pharmacol. 2009 Apr;63(5):889-901. doi: 10.1007/s00280-008-0812-9. Epub 2008 Aug 5. Cancer Chemother Pharmacol. 2009. PMID: 18679685

2

Mode of action of the novel phenazine anticancer agents XR11576 and XR5944.

Lewis LJ, Mistry P, Charlton PA, Thomas H, Coley HM. Lewis LJ, et al. Among authors: mistry p. Anticancer Drugs. 2007 Feb;18(2):139-48. doi: 10.1097/CAD.0b013e328010772f. Anticancer Drugs. 2007. PMID: 17159600

3

Structure-activity relationships for analogues of the phenazine-based dual topoisomerase I/II inhibitor XR11576.

Wang S, Miller W, Milton J, Vicker N, Stewart A, Charlton P, Mistry P, Hardick D, Denny WA. Wang S, et al. Among authors: mistry p. Bioorg Med Chem Lett. 2002 Feb 11;12(3):415-8. doi: 10.1016/s0960-894x(01)00770-3. Bioorg Med Chem Lett. 2002. PMID: 11814810

4

In vitro and in vivo characterization of XR11576, a novel, orally active, dual inhibitor of topoisomerase I and II.

Mistry P, Stewart AJ, Dangerfield W, Baker M, Liddle C, Bootle D, Kofler B, Laurie D, Denny WA, Baguley B, Charlton PA. Mistry P, et al. Anticancer Drugs. 2002 Jan;13(1):15-28. doi: 10.1097/00001813-200201000-00002. Anticancer Drugs. 2002. PMID: 11914637

5

Preclinical anti-tumor activity of XR5944 in combination with carboplatin or doxorubicin in non-small-cell lung carcinoma.

Harris SM, Scott JA, Brown JL, Charlton PA, Mistry P. Harris SM, et al. Among authors: mistry p. Anticancer Drugs. 2005 Oct;16(9):945-51. doi: 10.1097/01.cad.0000176499.17939.56. Anticancer Drugs. 2005. PMID: 16162971

6

Antitumour activity of XR5944 in vitro and in vivo in combination with 5-fluorouracil and irinotecan in colon cancer cell lines.

Harris SM, Mistry P, Freathy C, Brown JL, Charlton PA. Harris SM, et al. Among authors: mistry p. Br J Cancer. 2005 Feb 28;92(4):722-8. doi: 10.1038/sj.bjc.6602403. Br J Cancer. 2005. PMID: 15700035 Free PMC article.

7

Antitumor activity of XR5944, a novel and potent topoisomerase poison.

Stewart AJ, Mistry P, Dangerfield W, Bootle D, Baker M, Kofler B, Okiji S, Baguley BC, Denny WA, Charlton PA. Stewart AJ, et al. Among authors: mistry p. Anticancer Drugs. 2001 Apr;12(4):359-67. doi: 10.1097/00001813-200104000-00009. Anticancer Drugs. 2001. PMID: 11335793

8

Novel angular benzophenazines: dual topoisomerase I and topoisomerase II inhibitors as potential anticancer agents.

Vicker N, Burgess L, Chuckowree IS, Dodd R, Folkes AJ, Hardick DJ, Hancox TC, Miller W, Milton J, Sohal S, Wang S, Wren SP, Charlton PA, Dangerfield W, Liddle C, Mistry P, Stewart AJ, Denny WA. Vicker N, et al. Among authors: mistry p. J Med Chem. 2002 Jan 31;45(3):721-39. doi: 10.1021/jm010329a. J Med Chem. 2002. PMID: 11806724

9

In vivo efficacy of XR9051, a potent modulator of P-glycoprotein mediated multidrug resistance.

Mistry P, Plumb J, Eccles S, Watson S, Dale I, Ryder H, Box G, Charlton P, Templeton D, Bevan PB. Mistry P, et al. Br J Cancer. 1999 Apr;79(11-12):1672-8. doi: 10.1038/sj.bjc.6690267. Br J Cancer. 1999. PMID: 10206276 Free PMC article.

10

Reversal of P-glycoprotein-mediated multidrug resistance by XR9051, a novel diketopiperazine derivative.

Dale IL, Tuffley W, Callaghan R, Holmes JA, Martin K, Luscombe M, Mistry P, Ryder H, Stewart AJ, Charlton P, Twentyman PR, Bevan P. Dale IL, et al. Among authors: mistry p. Br J Cancer. 1998 Oct;78(7):885-92. doi: 10.1038/bjc.1998.597. Br J Cancer. 1998. PMID: 9764579 Free PMC article.

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