Simanek EE - Search Results

1

The role of the size and number of polyethylene glycol chains in the biodistribution and tumor localization of triazine dendrimers.

Lim J, Guo Y, Rostollan CL, Stanfield J, Hsieh JT, Sun X, Simanek EE. Lim J, et al. Among authors: simanek ee. Mol Pharm. 2008 Jul-Aug;5(4):540-7. doi: 10.1021/mp8000292. Mol Pharm. 2008. PMID: 18672950

2

In vitro and in vivo evaluation of a melamine dendrimer as a vehicle for drug delivery.

Neerman MF, Zhang W, Parrish AR, Simanek EE. Neerman MF, et al. Among authors: simanek ee. Int J Pharm. 2004 Aug 20;281(1-2):129-32. doi: 10.1016/j.ijpharm.2004.04.023. Int J Pharm. 2004. PMID: 15288350 Review.

3

Cytotoxicity, hemolysis, and acute in vivo toxicity of dendrimers based on melamine, candidate vehicles for drug delivery.

Chen HT, Neerman MF, Parrish AR, Simanek EE. Chen HT, et al. Among authors: simanek ee. J Am Chem Soc. 2004 Aug 18;126(32):10044-8. doi: 10.1021/ja048548j. J Am Chem Soc. 2004. PMID: 15303879

4

Reduction of drug toxicity using dendrimers based on melamine.

Neerman MF, Chen HT, Parrish AR, Simanek EE. Neerman MF, et al. Among authors: simanek ee. Mol Pharm. 2004 Sep-Oct;1(5):390-3. doi: 10.1021/mp049957p. Mol Pharm. 2004. PMID: 16026011

5

Toward the next-generation drug delivery vehicle: synthesis of a dendrimer with four orthogonally reactive groups.

Lim J, Simanek EE. Lim J, et al. Among authors: simanek ee. Mol Pharm. 2005 Jul-Aug;2(4):273-7. doi: 10.1021/mp050030e. Mol Pharm. 2005. PMID: 16053330

6

Triazine dendrimers with orthogonally protected amines on the periphery. Masking amines with Dde and BOC groups provides an alternative to carrying protected alcohols and disulfides through an iterative synthesis.

Umali AP, Crampton HL, Simanek EE. Umali AP, et al. Among authors: simanek ee. J Org Chem. 2007 Dec 21;72(26):9866-74. doi: 10.1021/jo701320h. Epub 2007 Dec 1. J Org Chem. 2007. PMID: 18052073

7

Synthesis of water-soluble dendrimers based on melamine bearing 16 paclitaxel groups.

Lim J, Simanek EE. Lim J, et al. Among authors: simanek ee. Org Lett. 2008 Jan 17;10(2):201-4. doi: 10.1021/ol7024907. Epub 2007 Dec 19. Org Lett. 2008. PMID: 18088131

8

Kilogram-scale synthesis of a second-generation dendrimer based on 1,3,5-triazine using green and industrially compatible methods with a single chromatographic step.

Chouai A, Simanek EE. Chouai A, et al. Among authors: simanek ee. J Org Chem. 2008 Mar 21;73(6):2357-66. doi: 10.1021/jo702462t. Epub 2008 Feb 29. J Org Chem. 2008. PMID: 18307354

9

Biodistribution of nanomedicines.

Simanek E, Patri AK. Simanek E, et al. Mol Pharm. 2008 Jul-Aug;5(4):473. doi: 10.1021/mp800083a. Mol Pharm. 2008. PMID: 18672948 No abstract available.

10

Intercepting the synthesis of triazine dendrimers with nucleophilic pharmacophores: a general strategy toward drug delivery vehicles.

Venditto VJ, Allred K, Allred CD, Simanek EE. Venditto VJ, et al. Among authors: simanek ee. Chem Commun (Camb). 2009 Oct 7;(37):5541-2. doi: 10.1039/b911353c. Epub 2009 Aug 11. Chem Commun (Camb). 2009. PMID: 19753350 Free PMC article.

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