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Page 1
Engineering GPCR signaling pathways with RASSLs.
Conklin BR, Hsiao EC, Claeysen S, Dumuis A, Srinivasan S, Forsayeth JR, Guettier JM, Chang WC, Pei Y, McCarthy KD, Nissenson RA, Wess J, Bockaert J, Roth BL. Conklin BR, et al. Among authors: roth bl. Nat Methods. 2008 Aug;5(8):673-8. doi: 10.1038/nmeth.1232. Nat Methods. 2008. PMID: 18668035 Free PMC article. Review.
Relating protein pharmacology by ligand chemistry.
Keiser MJ, Roth BL, Armbruster BN, Ernsberger P, Irwin JJ, Shoichet BK. Keiser MJ, et al. Among authors: roth bl. Nat Biotechnol. 2007 Feb;25(2):197-206. doi: 10.1038/nbt1284. Nat Biotechnol. 2007. PMID: 17287757 Free article.
Engineered GPCRs as tools to modulate signal transduction.
Pei Y, Rogan SC, Yan F, Roth BL. Pei Y, et al. Among authors: roth bl. Physiology (Bethesda). 2008 Dec;23:313-21. doi: 10.1152/physiol.00025.2008. Physiology (Bethesda). 2008. PMID: 19074739 Free article. Review.
A chemical-genetic approach to study G protein regulation of beta cell function in vivo.
Guettier JM, Gautam D, Scarselli M, Ruiz de Azua I, Li JH, Rosemond E, Ma X, Gonzalez FJ, Armbruster BN, Lu H, Roth BL, Wess J. Guettier JM, et al. Among authors: roth bl. Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19197-202. doi: 10.1073/pnas.0906593106. Epub 2009 Oct 26. Proc Natl Acad Sci U S A. 2009. PMID: 19858481 Free PMC article.
Predicting new molecular targets for known drugs.
Keiser MJ, Setola V, Irwin JJ, Laggner C, Abbas AI, Hufeisen SJ, Jensen NH, Kuijer MB, Matos RC, Tran TB, Whaley R, Glennon RA, Hert J, Thomas KL, Edwards DD, Shoichet BK, Roth BL. Keiser MJ, et al. Among authors: roth bl. Nature. 2009 Nov 12;462(7270):175-81. doi: 10.1038/nature08506. Epub 2009 Nov 1. Nature. 2009. PMID: 19881490 Free PMC article.
547 results