Type I IFN induces long-chain acyl-CoA synthetase 1 to generate a phosphatidic acid reservoir for lipotoxic saturated fatty acids.
Barnhart S, Shimizu-Albergine M, Kedar E, Kothari V, Shao B, Krueger M, Hsu CC, Tang J, Kanter JE, Kramer F, Djukovic D, Pascua V, Loo YM, Colonna L, Van den Bogaerde SJ, An J, Gale M Jr, Reue K, Fisher EA, Gharib SA, Elkon KB, Bornfeldt KE.
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J Lipid Res. 2024 Dec 13:100730. doi: 10.1016/j.jlr.2024.100730. Online ahead of print.
J Lipid Res. 2024.
PMID: 39675509
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