Harrigan JA - Search Results

1

WRN Exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand.

Bukowy Z, Harrigan JA, Ramsden DA, Tudek B, Bohr VA, Stevnsner T. Bukowy Z, et al. Among authors: harrigan ja. Nucleic Acids Res. 2008 Sep;36(15):4975-87. doi: 10.1093/nar/gkn468. Epub 2008 Jul 25. Nucleic Acids Res. 2008. PMID: 18658245 Free PMC article.

2

Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein.

von Kobbe C, Harrigan JA, Schreiber V, Stiegler P, Piotrowski J, Dawut L, Bohr VA. von Kobbe C, et al. Among authors: harrigan ja. Nucleic Acids Res. 2004 Aug 3;32(13):4003-14. doi: 10.1093/nar/gkh721. Print 2004. Nucleic Acids Res. 2004. PMID: 15292449 Free PMC article.

3

The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase beta.

Harrigan JA, Wilson DM 3rd, Prasad R, Opresko PL, Beck G, May A, Wilson SH, Bohr VA. Harrigan JA, et al. Nucleic Acids Res. 2006 Jan 30;34(2):745-54. doi: 10.1093/nar/gkj475. Print 2006. Nucleic Acids Res. 2006. PMID: 16449207 Free PMC article.

4

WRN exonuclease activity is blocked by DNA termini harboring 3' obstructive groups.

Harrigan JA, Fan J, Momand J, Perrino FW, Bohr VA, Wilson DM 3rd. Harrigan JA, et al. Mech Ageing Dev. 2007 Mar;128(3):259-66. doi: 10.1016/j.mad.2006.12.005. Epub 2006 Dec 20. Mech Ageing Dev. 2007. PMID: 17224176 Free PMC article.

5

Human diseases deficient in RecQ helicases.

Harrigan JA, Bohr VA. Harrigan JA, et al. Biochimie. 2003 Nov;85(11):1185-93. doi: 10.1016/j.biochi.2003.10.006. Biochimie. 2003. PMID: 14726023

6

The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity.

Harrigan JA, Opresko PL, von Kobbe C, Kedar PS, Prasad R, Wilson SH, Bohr VA. Harrigan JA, et al. J Biol Chem. 2003 Jun 20;278(25):22686-95. doi: 10.1074/jbc.M213103200. Epub 2003 Mar 27. J Biol Chem. 2003. PMID: 12665521 Free article.

7

Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.

Opresko PL, Cheng WH, von Kobbe C, Harrigan JA, Bohr VA. Opresko PL, et al. Among authors: harrigan ja. Carcinogenesis. 2003 May;24(5):791-802. doi: 10.1093/carcin/bgg034. Carcinogenesis. 2003. PMID: 12771022 Review.

8

Central role for the Werner syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly(ADP-ribosyl)ation pathway after DNA damage.

von Kobbe C, Harrigan JA, May A, Opresko PL, Dawut L, Cheng WH, Bohr VA. von Kobbe C, et al. Among authors: harrigan ja. Mol Cell Biol. 2003 Dec;23(23):8601-13. doi: 10.1128/MCB.23.23.8601-8613.2003. Mol Cell Biol. 2003. PMID: 14612404 Free PMC article.

9

Werner protein stimulates topoisomerase I DNA relaxation activity.

Laine JP, Opresko PL, Indig FE, Harrigan JA, von Kobbe C, Bohr VA. Laine JP, et al. Among authors: harrigan ja. Cancer Res. 2003 Nov 1;63(21):7136-46. Cancer Res. 2003. PMID: 14612507

10

Werner syndrome protein 1367 variants and disposition towards coronary artery disease in Caucasian patients.

Bohr VA, Metter EJ, Harrigan JA, von Kobbe C, Liu JL, Gray MD, Majumdar A, Wilson DM 3rd, Seidman MM. Bohr VA, et al. Among authors: harrigan ja. Mech Ageing Dev. 2004 Jul;125(7):491-6. doi: 10.1016/j.mad.2004.05.001. Mech Ageing Dev. 2004. PMID: 15246744

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