Douglas P - Search Results

1

DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks.

Yu Y, Mahaney BL, Yano K, Ye R, Fang S, Douglas P, Chen DJ, Lees-Miller SP. Yu Y, et al. Among authors: douglas p. DNA Repair (Amst). 2008 Oct 1;7(10):1680-92. doi: 10.1016/j.dnarep.2008.06.015. Epub 2008 Aug 3. DNA Repair (Amst). 2008. PMID: 18644470 Free PMC article.

2

Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase.

Chan DW, Son SC, Block W, Ye R, Khanna KK, Wold MS, Douglas P, Goodarzi AA, Pelley J, Taya Y, Lavin MF, Lees-Miller SP. Chan DW, et al. Among authors: douglas p. J Biol Chem. 2000 Mar 17;275(11):7803-10. doi: 10.1074/jbc.275.11.7803. J Biol Chem. 2000. PMID: 10713094 Free article.

3

Protein phosphatases regulate DNA-dependent protein kinase activity.

Douglas P, Moorhead GB, Ye R, Lees-Miller SP. Douglas P, et al. J Biol Chem. 2001 Jun 1;276(22):18992-8. doi: 10.1074/jbc.M011703200. Epub 2001 Mar 16. J Biol Chem. 2001. PMID: 11376007 Free article.

4

Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase.

Douglas P, Sapkota GP, Morrice N, Yu Y, Goodarzi AA, Merkle D, Meek K, Alessi DR, Lees-Miller SP. Douglas P, et al. Biochem J. 2002 Nov 15;368(Pt 1):243-51. doi: 10.1042/BJ20020973. Biochem J. 2002. PMID: 12186630 Free PMC article.

5

The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation.

Merkle D, Douglas P, Moorhead GB, Leonenko Z, Yu Y, Cramb D, Bazett-Jones DP, Lees-Miller SP. Merkle D, et al. Among authors: douglas p. Biochemistry. 2002 Oct 22;41(42):12706-14. doi: 10.1021/bi0263558. Biochemistry. 2002. PMID: 12379113

6

Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair.

Ding Q, Reddy YV, Wang W, Woods T, Douglas P, Ramsden DA, Lees-Miller SP, Meek K. Ding Q, et al. Among authors: douglas p. Mol Cell Biol. 2003 Aug;23(16):5836-48. doi: 10.1128/MCB.23.16.5836-5848.2003. Mol Cell Biol. 2003. PMID: 12897153 Free PMC article.

7

Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.

Kurz EU, Douglas P, Lees-Miller SP. Kurz EU, et al. Among authors: douglas p. J Biol Chem. 2004 Dec 17;279(51):53272-81. doi: 10.1074/jbc.M406879200. Epub 2004 Oct 14. J Biol Chem. 2004. PMID: 15489221 Free article.

8

Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.

Goodarzi AA, Jonnalagadda JC, Douglas P, Young D, Ye R, Moorhead GB, Lees-Miller SP, Khanna KK. Goodarzi AA, et al. Among authors: douglas p. EMBO J. 2004 Nov 10;23(22):4451-61. doi: 10.1038/sj.emboj.7600455. Epub 2004 Oct 28. EMBO J. 2004. PMID: 15510216 Free PMC article.

9

Inhibition of homologous recombination by variants of the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs).

Convery E, Shin EK, Ding Q, Wang W, Douglas P, Davis LS, Nickoloff JA, Lees-Miller SP, Meek K. Convery E, et al. Among authors: douglas p. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1345-50. doi: 10.1073/pnas.0406466102. Epub 2005 Jan 24. Proc Natl Acad Sci U S A. 2005. PMID: 15668400 Free PMC article.

10

DNA-PK-dependent phosphorylation of Ku70/80 is not required for non-homologous end joining.

Douglas P, Gupta S, Morrice N, Meek K, Lees-Miller SP. Douglas P, et al. DNA Repair (Amst). 2005 Aug 15;4(9):1006-18. doi: 10.1016/j.dnarep.2005.05.003. DNA Repair (Amst). 2005. PMID: 15941674

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