Wermann M - Search Results

1

Inhibition of glutaminyl cyclase prevents pGlu-Abeta formation after intracortical/hippocampal microinjection in vivo/in situ.

Schilling S, Appl T, Hoffmann T, Cynis H, Schulz K, Jagla W, Friedrich D, Wermann M, Buchholz M, Heiser U, von Hörsten S, Demuth HU. Schilling S, et al. Among authors: wermann m. J Neurochem. 2008 Aug;106(3):1225-36. doi: 10.1111/j.1471-4159.2008.05471.x. Epub 2008 Jul 8. J Neurochem. 2008. PMID: 18627432 Free article.

2

Continuous spectrometric assays for glutaminyl cyclase activity.

Schilling S, Hoffmann T, Wermann M, Heiser U, Wasternack C, Demuth HU. Schilling S, et al. Among authors: wermann m. Anal Biochem. 2002 Apr 1;303(1):49-56. doi: 10.1006/abio.2001.5560. Anal Biochem. 2002. PMID: 11906150

3

The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism.

Engel M, Hoffmann T, Wagner L, Wermann M, Heiser U, Kiefersauer R, Huber R, Bode W, Demuth HU, Brandstetter H. Engel M, et al. Among authors: wermann m. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5063-8. doi: 10.1073/pnas.0230620100. Epub 2003 Apr 10. Proc Natl Acad Sci U S A. 2003. PMID: 12690074 Free PMC article.

4

Identification of human glutaminyl cyclase as a metalloenzyme. Potent inhibition by imidazole derivatives and heterocyclic chelators.

Schilling S, Niestroj AJ, Rahfeld JU, Hoffmann T, Wermann M, Zunkel K, Wasternack C, Demuth HU. Schilling S, et al. Among authors: wermann m. J Biol Chem. 2003 Dec 12;278(50):49773-9. doi: 10.1074/jbc.M309077200. Epub 2003 Sep 30. J Biol Chem. 2003. PMID: 14522962 Free article.

5

Characterisation of human dipeptidyl peptidase IV expressed in Pichia pastoris. A structural and mechanistic comparison between the recombinant human and the purified porcine enzyme.

Bär J, Weber A, Hoffmann T, Stork J, Wermann M, Wagner L, Aust S, Gerhartz B, Demuth HU. Bär J, et al. Among authors: wermann m. Biol Chem. 2003 Dec;384(12):1553-63. doi: 10.1515/BC.2003.172. Biol Chem. 2003. PMID: 14719797

6

Isolation, catalytic properties, and competitive inhibitors of the zinc-dependent murine glutaminyl cyclase.

Schilling S, Cynis H, von Bohlen A, Hoffmann T, Wermann M, Heiser U, Buchholz M, Zunkel K, Demuth HU. Schilling S, et al. Among authors: wermann m. Biochemistry. 2005 Oct 11;44(40):13415-24. doi: 10.1021/bi051142e. Biochemistry. 2005. PMID: 16201766

7

Isolation and characterization of the glutaminyl cyclases from Solanum tuberosum and Arabidopsis thaliana: implications for physiological functions.

Schilling S, Stenzel I, von Bohlen A, Wermann M, Schulz K, Demuth HU, Wasternack C. Schilling S, et al. Among authors: wermann m. Biol Chem. 2007 Feb;388(2):145-53. doi: 10.1515/BC.2007.016. Biol Chem. 2007. PMID: 17261077

8

Does human attractin have DP4 activity?

Friedrich D, Hoffmann T, Bär J, Wermann M, Manhart S, Heiser U, Demuth HU. Friedrich D, et al. Among authors: wermann m. Biol Chem. 2007 Feb;388(2):155-62. doi: 10.1515/BC.2007.017. Biol Chem. 2007. PMID: 17261078

9

Isolation and characterization of glutaminyl cyclases from Drosophila: evidence for enzyme forms with different subcellular localization.

Schilling S, Lindner C, Koch B, Wermann M, Rahfeld JU, von Bohlen A, Rudolph T, Reuter G, Demuth HU. Schilling S, et al. Among authors: wermann m. Biochemistry. 2007 Sep 25;46(38):10921-30. doi: 10.1021/bi701043x. Epub 2007 Aug 28. Biochemistry. 2007. PMID: 17722885

10

Isolation of an isoenzyme of human glutaminyl cyclase: retention in the Golgi complex suggests involvement in the protein maturation machinery.

Cynis H, Rahfeld JU, Stephan A, Kehlen A, Koch B, Wermann M, Demuth HU, Schilling S. Cynis H, et al. Among authors: wermann m. J Mol Biol. 2008 Jun 20;379(5):966-80. doi: 10.1016/j.jmb.2008.03.078. Epub 2008 Apr 15. J Mol Biol. 2008. PMID: 18486145

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