Martin L - Search Results

1

Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein.

Stricher F, Huang CC, Descours A, Duquesnoy S, Combes O, Decker JM, Kwon YD, Lusso P, Shaw GM, Vita C, Kwong PD, Martin L. Stricher F, et al. Among authors: martin l. J Mol Biol. 2008 Oct 3;382(2):510-24. doi: 10.1016/j.jmb.2008.06.069. Epub 2008 Jul 1. J Mol Biol. 2008. PMID: 18619974 Free PMC article.

2

Design of miniproteins by the transfer of active sites onto small-size scaffolds.

Stricher F, Martin L, Vita C. Stricher F, et al. Among authors: martin l. Methods Mol Biol. 2006;340:113-49. doi: 10.1385/1-59745-116-9:113. Methods Mol Biol. 2006. PMID: 16957335 Review.

3

A simple one-step method for the preparation of HIV-1 envelope glycoprotein immunogens based on a CD4 mimic peptide.

Martin G, Sun Y, Heyd B, Combes O, Ulmer JB, Descours A, Barnett SW, Srivastava IK, Martin L. Martin G, et al. Among authors: martin l. Virology. 2008 Nov 25;381(2):241-50. doi: 10.1016/j.virol.2008.08.039. Epub 2008 Oct 2. Virology. 2008. PMID: 18835005 Free PMC article.

4

Interfacial cavity filling to optimize CD4-mimetic miniprotein interactions with HIV-1 surface glycoprotein.

Morellato-Castillo L, Acharya P, Combes O, Michiels J, Descours A, Ramos OH, Yang Y, Vanham G, Ariën KK, Kwong PD, Martin L, Kessler P. Morellato-Castillo L, et al. Among authors: martin l. J Med Chem. 2013 Jun 27;56(12):5033-47. doi: 10.1021/jm4002988. Epub 2013 Jun 11. J Med Chem. 2013. PMID: 23710622 Free PMC article.

5

Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes.

Martin L, Stricher F, Missé D, Sironi F, Pugnière M, Barthe P, Prado-Gotor R, Freulon I, Magne X, Roumestand C, Ménez A, Lusso P, Veas F, Vita C. Martin L, et al. Nat Biotechnol. 2003 Jan;21(1):71-6. doi: 10.1038/nbt768. Epub 2002 Dec 16. Nat Biotechnol. 2003. PMID: 12483221

6

A high-throughput fluorescence polarization assay specific to the CD4 binding site of HIV-1 glycoproteins based on a fluorescein-labelled CD4 mimic.

Stricher F, Martin L, Barthe P, Pogenberg V, Mechulam A, Menez A, Roumestand C, Veas F, Royer C, Vita C. Stricher F, et al. Among authors: martin l. Biochem J. 2005 Aug 15;390(Pt 1):29-39. doi: 10.1042/BJ20041953. Biochem J. 2005. PMID: 15836438 Free PMC article.

7

Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth.

Huang CC, Stricher F, Martin L, Decker JM, Majeed S, Barthe P, Hendrickson WA, Robinson J, Roumestand C, Sodroski J, Wyatt R, Shaw GM, Vita C, Kwong PD. Huang CC, et al. Among authors: martin l. Structure. 2005 May;13(5):755-68. doi: 10.1016/j.str.2005.03.006. Structure. 2005. PMID: 15893666 Free article.

8

Stabilization of HIV-1 envelope in the CD4-bound conformation through specific cross-linking of a CD4 mimetic.

Martin G, Burke B, Thaï R, Dey AK, Combes O, Ramos OH, Heyd B, Geonnotti AR, Montefiori DC, Kan E, Lian Y, Sun Y, Abache T, Ulmer JB, Madaoui H, Guérois R, Barnett SW, Srivastava IK, Kessler P, Martin L. Martin G, et al. Among authors: martin l. J Biol Chem. 2011 Jun 17;286(24):21706-16. doi: 10.1074/jbc.M111.232272. Epub 2011 Apr 12. J Biol Chem. 2011. PMID: 21487012 Free PMC article.

9

Structural basis for highly effective HIV-1 neutralization by CD4-mimetic miniproteins revealed by 1.5 Å cocrystal structure of gp120 and M48U1.

Acharya P, Luongo TS, Louder MK, McKee K, Yang Y, Kwon YD, Mascola JR, Kessler P, Martin L, Kwong PD. Acharya P, et al. Among authors: martin l. Structure. 2013 Jun 4;21(6):1018-29. doi: 10.1016/j.str.2013.04.015. Epub 2013 May 23. Structure. 2013. PMID: 23707685 Free PMC article.

10

Structural definition of an antibody-dependent cellular cytotoxicity response implicated in reduced risk for HIV-1 infection.

Acharya P, Tolbert WD, Gohain N, Wu X, Yu L, Liu T, Huang W, Huang CC, Kwon YD, Louder RK, Luongo TS, McLellan JS, Pancera M, Yang Y, Zhang B, Flinko R, Foulke JS Jr, Sajadi MM, Kamin-Lewis R, Robinson JE, Martin L, Kwong PD, Guan Y, DeVico AL, Lewis GK, Pazgier M. Acharya P, et al. Among authors: martin l. J Virol. 2014 Nov;88(21):12895-906. doi: 10.1128/JVI.02194-14. Epub 2014 Aug 27. J Virol. 2014. PMID: 25165110 Free PMC article.

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