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S1P, dihydro-S1P and C24:1-ceramide levels in the HDL-containing fraction of serum inversely correlate with occurrence of ischemic heart disease.
Argraves KM, Sethi AA, Gazzolo PJ, Wilkerson BA, Remaley AT, Tybjaerg-Hansen A, Nordestgaard BG, Yeatts SD, Nicholas KS, Barth JL, Argraves WS. Argraves KM, et al. Among authors: wilkerson ba. Lipids Health Dis. 2011 May 9;10:70. doi: 10.1186/1476-511X-10-70. Lipids Health Dis. 2011. PMID: 21554699 Free PMC article.
Sphingosine 1-phosphate (S1P) carrier-dependent regulation of endothelial barrier: high density lipoprotein (HDL)-S1P prolongs endothelial barrier enhancement as compared with albumin-S1P via effects on levels, trafficking, and signaling of S1P1.
Wilkerson BA, Grass GD, Wing SB, Argraves WS, Argraves KM. Wilkerson BA, et al. J Biol Chem. 2012 Dec 28;287(53):44645-53. doi: 10.1074/jbc.M112.423426. Epub 2012 Nov 7. J Biol Chem. 2012. PMID: 23135269 Free PMC article.
Cubilin maintains blood levels of HDL and albumin.
Aseem O, Smith BT, Cooley MA, Wilkerson BA, Argraves KM, Remaley AT, Argraves WS. Aseem O, et al. Among authors: wilkerson ba. J Am Soc Nephrol. 2014 May;25(5):1028-36. doi: 10.1681/ASN.2013060671. Epub 2013 Dec 19. J Am Soc Nephrol. 2014. PMID: 24357674 Free PMC article.
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