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Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition.
Nickeleit I, Zender S, Sasse F, Geffers R, Brandes G, Sörensen I, Steinmetz H, Kubicka S, Carlomagno T, Menche D, Gütgemann I, Buer J, Gossler A, Manns MP, Kalesse M, Frank R, Malek NP. Nickeleit I, et al. Among authors: frank r. Cancer Cell. 2008 Jul 8;14(1):23-35. doi: 10.1016/j.ccr.2008.05.016. Cancer Cell. 2008. PMID: 18598941 Free article.
Synthesis and biological characterization of argyrin F.
Bülow L, Nickeleit I, Girbig AK, Brodmann T, Rentsch A, Eggert U, Sasse F, Steinmetz H, Frank R, Carlomagno T, Malek NP, Kalesse M. Bülow L, et al. Among authors: frank r. ChemMedChem. 2010 Jun 7;5(6):832-6. doi: 10.1002/cmdc.201000080. ChemMedChem. 2010. PMID: 20358576 No abstract available.
Investigations on the mode of action of gephyronic acid, an inhibitor of eukaryotic protein translation from myxobacteria.
Muthukumar Y, Münkemer J, Mathieu D, Richter C, Schwalbe H, Steinmetz H, Kessler W, Reichelt J, Beutling U, Frank R, Büssow K, van den Heuvel J, Brönstrup M, Taylor RE, Laschat S, Sasse F. Muthukumar Y, et al. Among authors: frank r. PLoS One. 2018 Jul 31;13(7):e0201605. doi: 10.1371/journal.pone.0201605. eCollection 2018. PLoS One. 2018. PMID: 30063768 Free PMC article.
Myxobacteria: natural pharmaceutical factories.
Diez J, Martinez JP, Mestres J, Sasse F, Frank R, Meyerhans A. Diez J, et al. Among authors: frank r. Microb Cell Fact. 2012 Apr 30;11:52. doi: 10.1186/1475-2859-11-52. Microb Cell Fact. 2012. PMID: 22545867 Free PMC article.
3,108 results