Spieker RS - Search Results

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Gamma-irradiation-induced DNA damage checkpoint activation involves feedback regulation between extracellular signal-regulated kinase 1/2 and BRCA1.

Yan Y, Black CP, Cao PT, Haferbier JL, Kolb RH, Spieker RS, Ristow AM, Cowan KH. Yan Y, et al. Among authors: spieker rs. Cancer Res. 2008 Jul 1;68(13):5113-21. doi: 10.1158/0008-5472.CAN-07-5818. Cancer Res. 2008. PMID: 18593910 Free PMC article.

BRCA1-mediated G2/M cell cycle arrest requires ERK1/2 kinase activation.

Yan Y, Spieker RS, Kim M, Stoeger SM, Cowan KH. Yan Y, et al. Among authors: spieker rs. Oncogene. 2005 May 5;24(20):3285-96. doi: 10.1038/sj.onc.1208492. Oncogene. 2005. PMID: 15735702

Brca1-deficient murine mammary epithelial cells have increased sensitivity to CDDP and MMS.

Sgagias MK, Wagner KU, Hamik B, Stoeger S, Spieker R, Huber LJ, Chodosh LA, Cowan KH. Sgagias MK, et al. Cell Cycle. 2004 Nov;3(11):1451-6. doi: 10.4161/cc.3.11.1211. Epub 2004 Nov 8. Cell Cycle. 2004. PMID: 15492509

The HER tyrosine kinase inhibitor CI1033 enhances cytotoxicity of 7-ethyl-10-hydroxycamptothecin and topotecan by inhibiting breast cancer resistance protein-mediated drug efflux.

Erlichman C, Boerner SA, Hallgren CG, Spieker R, Wang XY, James CD, Scheffer GL, Maliepaard M, Ross DD, Bible KC, Kaufmann SH. Erlichman C, et al. Cancer Res. 2001 Jan 15;61(2):739-48. Cancer Res. 2001. PMID: 11212277

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