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247 results

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Page 1
Algorithm for backrub motions in protein design.
Georgiev I, Keedy D, Richardson JS, Richardson DC, Donald BR. Georgiev I, et al. Bioinformatics. 2008 Jul 1;24(13):i196-204. doi: 10.1093/bioinformatics/btn169. Bioinformatics. 2008. PMID: 18586714 Free PMC article.
Dead-end elimination with backbone flexibility.
Georgiev I, Donald BR. Georgiev I, et al. Bioinformatics. 2007 Jul 1;23(13):i185-94. doi: 10.1093/bioinformatics/btm197. Bioinformatics. 2007. PMID: 17646295
Computational structure-based redesign of enzyme activity.
Chen CY, Georgiev I, Anderson AC, Donald BR. Chen CY, et al. Among authors: georgiev i. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3764-9. doi: 10.1073/pnas.0900266106. Epub 2009 Feb 19. Proc Natl Acad Sci U S A. 2009. PMID: 19228942 Free PMC article.
Predicting resistance mutations using protein design algorithms.
Frey KM, Georgiev I, Donald BR, Anderson AC. Frey KM, et al. Among authors: georgiev i. Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13707-12. doi: 10.1073/pnas.1002162107. Epub 2010 Jul 19. Proc Natl Acad Sci U S A. 2010. PMID: 20643959 Free PMC article.
The role of local backrub motions in evolved and designed mutations.
Keedy DA, Georgiev I, Triplett EB, Donald BR, Richardson DC, Richardson JS. Keedy DA, et al. Among authors: georgiev i. PLoS Comput Biol. 2012;8(8):e1002629. doi: 10.1371/journal.pcbi.1002629. Epub 2012 Aug 2. PLoS Comput Biol. 2012. PMID: 22876172 Free PMC article.
OSPREY: protein design with ensembles, flexibility, and provable algorithms.
Gainza P, Roberts KE, Georgiev I, Lilien RH, Keedy DA, Chen CY, Reza F, Anderson AC, Richardson DC, Richardson JS, Donald BR. Gainza P, et al. Among authors: georgiev i. Methods Enzymol. 2013;523:87-107. doi: 10.1016/B978-0-12-394292-0.00005-9. Methods Enzymol. 2013. PMID: 23422427 Free PMC article.
Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo.
Rudicell RS, Kwon YD, Ko SY, Pegu A, Louder MK, Georgiev IS, Wu X, Zhu J, Boyington JC, Chen X, Shi W, Yang ZY, Doria-Rose NA, McKee K, O'Dell S, Schmidt SD, Chuang GY, Druz A, Soto C, Yang Y, Zhang B, Zhou T, Todd JP, Lloyd KE, Eudailey J, Roberts KE, Donald BR, Bailer RT, Ledgerwood J; NISC Comparative Sequencing Program; Mullikin JC, Shapiro L, Koup RA, Graham BS, Nason MC, Connors M, Haynes BF, Rao SS, Roederer M, Kwong PD, Mascola JR, Nabel GJ. Rudicell RS, et al. J Virol. 2014 Nov;88(21):12669-82. doi: 10.1128/JVI.02213-14. Epub 2014 Aug 20. J Virol. 2014. PMID: 25142607 Free PMC article.
247 results