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Toxicology study of repeat intracerebral administration of a measles virus derivative producing carcinoembryonic antigen in rhesus macaques in support of a phase I/II clinical trial for patients with recurrent gliomas.
Myers R, Harvey M, Kaufmann TJ, Greiner SM, Krempski JW, Raffel C, Shelton SE, Soeffker D, Zollman P, Federspiel MJ, Blanco M, Galanis E. Myers R, et al. Among authors: galanis e. Hum Gene Ther. 2008 Jul;19(7):690-8. doi: 10.1089/hum.2008.035. Hum Gene Ther. 2008. PMID: 18576918 Free PMC article.
We have previously demonstrated that oncolytic measles virus strains derived from the Edmonston vaccine lineage have significant antitumor activity against gliomas [Phuong, L.K., Allen, C., Peng, K.W., Giannini, C., Greiner, S., Teneyck, C.J., Mishra, P.K., Macura, S.I., Russell, …
We have previously demonstrated that oncolytic measles virus strains derived from the Edmonston vaccine lineage have significant antitumor a …
Retargeted oncolytic measles strains entering via the EGFRvIII receptor maintain significant antitumor activity against gliomas with increased tumor specificity.
Allen C, Vongpunsawad S, Nakamura T, James CD, Schroeder M, Cattaneo R, Giannini C, Krempski J, Peng KW, Goble JM, Uhm JH, Russell SJ, Galanis E. Allen C, et al. Among authors: galanis e. Cancer Res. 2006 Dec 15;66(24):11840-50. doi: 10.1158/0008-5472.CAN-06-1200. Cancer Res. 2006. PMID: 17178881
364 results