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23 results

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Page 1
Antibody fucosylation differentially impacts cytotoxicity mediated by NK and PMN effector cells.
Peipp M, Lammerts van Bueren JJ, Schneider-Merck T, Bleeker WW, Dechant M, Beyer T, Repp R, van Berkel PH, Vink T, van de Winkel JG, Parren PW, Valerius T. Peipp M, et al. Among authors: van berkel ph, lammerts van bueren jj, van de winkel jg. Blood. 2008 Sep 15;112(6):2390-9. doi: 10.1182/blood-2008-03-144600. Epub 2008 Jun 19. Blood. 2008. PMID: 18566325 Free article.
Human IgG2 antibodies against epidermal growth factor receptor effectively trigger antibody-dependent cellular cytotoxicity but, in contrast to IgG1, only by cells of myeloid lineage.
Schneider-Merck T, Lammerts van Bueren JJ, Berger S, Rossen K, van Berkel PH, Derer S, Beyer T, Lohse S, Bleeker WK, Peipp M, Parren PW, van de Winkel JG, Valerius T, Dechant M. Schneider-Merck T, et al. Among authors: van berkel ph, lammerts van bueren jj, van de winkel jg. J Immunol. 2010 Jan 1;184(1):512-20. doi: 10.4049/jimmunol.0900847. Epub 2009 Nov 30. J Immunol. 2010. PMID: 19949082
Complement-mediated tumor-specific cell lysis by antibody combinations targeting epidermal growth factor receptor (EGFR) and its variant III (EGFRvIII).
Klausz K, Berger S, Lammerts van Bueren JJ, Derer S, Lohse S, Dechant M, van de Winkel JG, Peipp M, Parren PW, Valerius T. Klausz K, et al. Among authors: lammerts van bueren jj, van de winkel jg. Cancer Sci. 2011 Oct;102(10):1761-8. doi: 10.1111/j.1349-7006.2011.02019.x. Epub 2011 Aug 4. Cancer Sci. 2011. PMID: 21718386 Free article.
Human kappa light chain targeted Pseudomonas exotoxin A--identifying human antibodies and Fab fragments with favorable characteristics for antibody-drug conjugate development.
Kellner C, Bleeker WK, Lammerts van Bueren JJ, Staudinger M, Klausz K, Derer S, Glorius P, Muskulus A, de Goeij BE, van de Winkel JG, Parren PW, Valerius T, Gramatzki M, Peipp M. Kellner C, et al. Among authors: lammerts van bueren jj, van de winkel jg. J Immunol Methods. 2011 Aug 31;371(1-2):122-33. doi: 10.1016/j.jim.2011.06.023. Epub 2011 Jun 30. J Immunol Methods. 2011. PMID: 21756911
Oncogenic KRAS impairs EGFR antibodies' efficiency by C/EBPβ-dependent suppression of EGFR expression.
Derer S, Berger S, Schlaeth M, Schneider-Merck T, Klausz K, Lohse S, Overdijk MB, Dechant M, Kellner C, Nagelmeier I, Scheel AH, Lammerts van Bueren JJ, van de Winkel JG, Parren PW, Peipp M, Valerius T. Derer S, et al. Among authors: lammerts van bueren jj. Neoplasia. 2012 Mar;14(3):190-205. doi: 10.1593/neo.111636. Neoplasia. 2012. PMID: 22496619 Free PMC article.
Epidermal growth factor receptor (EGFR) antibody-induced antibody-dependent cellular cytotoxicity plays a prominent role in inhibiting tumorigenesis, even of tumor cells insensitive to EGFR signaling inhibition.
Overdijk MB, Verploegen S, van den Brakel JH, Lammerts van Bueren JJ, Vink T, van de Winkel JG, Parren PW, Bleeker WK. Overdijk MB, et al. Among authors: lammerts van bueren jj, van den brakel jh, van de winkel jg. J Immunol. 2011 Sep 15;187(6):3383-90. doi: 10.4049/jimmunol.1003926. Epub 2011 Aug 10. J Immunol. 2011. PMID: 21832160 Free article.
Novel human antibody therapeutics: the age of the Umabs.
Ruuls SR, Lammerts van Bueren JJ, van de Winkel JG, Parren PW. Ruuls SR, et al. Among authors: lammerts van bueren jj, van de winkel jg. Biotechnol J. 2008 Oct;3(9-10):1157-71. doi: 10.1002/biot.200800110. Biotechnol J. 2008. PMID: 18702090 Free PMC article. Review.
23 results