Tydlacka S - Search Results

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Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease.

Wang CE, Tydlacka S, Orr AL, Yang SH, Graham RK, Hayden MR, Li S, Chan AW, Li XJ. Wang CE, et al. Among authors: tydlacka s. Hum Mol Genet. 2008 Sep 1;17(17):2738-51. doi: 10.1093/hmg/ddn175. Epub 2008 Jun 16. Hum Mol Genet. 2008. PMID: 18558632 Free PMC article.

Impaired ubiquitin-proteasome system activity in the synapses of Huntington's disease mice.

Wang J, Wang CE, Orr A, Tydlacka S, Li SH, Li XJ. Wang J, et al. Among authors: tydlacka s. J Cell Biol. 2008 Mar 24;180(6):1177-89. doi: 10.1083/jcb.200709080. J Cell Biol. 2008. PMID: 18362179 Free PMC article.

Differential activities of the ubiquitin-proteasome system in neurons versus glia may account for the preferential accumulation of misfolded proteins in neurons.

Tydlacka S, Wang CE, Wang X, Li S, Li XJ. Tydlacka S, et al. J Neurosci. 2008 Dec 3;28(49):13285-95. doi: 10.1523/JNEUROSCI.4393-08.2008. J Neurosci. 2008. PMID: 19052220 Free PMC article.

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