Parrott N - Search Results

1

Applications of physiologically based absorption models in drug discovery and development.

Parrott N, Lave T. Parrott N, et al. Mol Pharm. 2008 Sep-Oct;5(5):760-75. doi: 10.1021/mp8000155. Epub 2008 Jun 12. Mol Pharm. 2008. PMID: 18547054

2

Prediction of intestinal absorption: comparative assessment of GASTROPLUS and IDEA.

Parrott N, Lavé T. Parrott N, et al. Eur J Pharm Sci. 2002 Oct;17(1-2):51-61. doi: 10.1016/s0928-0987(02)00132-x. Eur J Pharm Sci. 2002. PMID: 12356420

3

Application of full physiological models for pharmaceutical drug candidate selection and extrapolation of pharmacokinetics to man.

Parrott N, Jones H, Paquereau N, Lavé T. Parrott N, et al. Basic Clin Pharmacol Toxicol. 2005 Mar;96(3):193-9. doi: 10.1111/j.1742-7843.2005.pto960308.x. Basic Clin Pharmacol Toxicol. 2005. PMID: 15733214 Free article.

4

An evaluation of the utility of physiologically based models of pharmacokinetics in early drug discovery.

Parrott N, Paquereau N, Coassolo P, Lavé T. Parrott N, et al. J Pharm Sci. 2005 Oct;94(10):2327-43. doi: 10.1002/jps.20419. J Pharm Sci. 2005. PMID: 16136543

5

A strategy for preclinical formulation development using GastroPlus as pharmacokinetic simulation tool and a statistical screening design applied to a dog study.

Kuentz M, Nick S, Parrott N, Röthlisberger D. Kuentz M, et al. Among authors: parrott n. Eur J Pharm Sci. 2006 Jan;27(1):91-9. doi: 10.1016/j.ejps.2005.08.011. Epub 2005 Oct 10. Eur J Pharm Sci. 2006. PMID: 16219449

6

A novel strategy for physiologically based predictions of human pharmacokinetics.

Jones HM, Parrott N, Jorga K, Lavé T. Jones HM, et al. Among authors: parrott n. Clin Pharmacokinet. 2006;45(5):511-42. doi: 10.2165/00003088-200645050-00006. Clin Pharmacokinet. 2006. PMID: 16640456

7

Predicting pharmacokinetic food effects using biorelevant solubility media and physiologically based modelling.

Jones HM, Parrott N, Ohlenbusch G, Lavé T. Jones HM, et al. Among authors: parrott n. Clin Pharmacokinet. 2006;45(12):1213-26. doi: 10.2165/00003088-200645120-00006. Clin Pharmacokinet. 2006. PMID: 17112297

8

Challenges and opportunities with modelling and simulation in drug discovery and drug development.

Lavé T, Parrott N, Grimm HP, Fleury A, Reddy M. Lavé T, et al. Among authors: parrott n. Xenobiotica. 2007 Oct-Nov;37(10-11):1295-310. doi: 10.1080/00498250701534885. Xenobiotica. 2007. PMID: 17968746

9

Predicting pharmacokinetics of drugs using physiologically based modeling--application to food effects.

Parrott N, Lukacova V, Fraczkiewicz G, Bolger MB. Parrott N, et al. AAPS J. 2009 Mar;11(1):45-53. doi: 10.1208/s12248-008-9079-7. Epub 2009 Jan 29. AAPS J. 2009. PMID: 19184451 Free PMC article. Review.

10

Development of a physiologically based model for oseltamivir and simulation of pharmacokinetics in neonates and infants.

Parrott N, Davies B, Hoffmann G, Koerner A, Lave T, Prinssen E, Theogaraj E, Singer T. Parrott N, et al. Clin Pharmacokinet. 2011 Sep;50(9):613-23. doi: 10.2165/11592640-000000000-00000. Clin Pharmacokinet. 2011. PMID: 21827216

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