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Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells.
Viparelli F, Cassese A, Doti N, Paturzo F, Marasco D, Dathan NA, Monti SM, Basile G, Ungaro P, Sabatella M, Miele C, Teperino R, Consiglio E, Pedone C, Beguinot F, Formisano P, Ruvo M. Viparelli F, et al. J Biol Chem. 2008 Aug 1;283(31):21769-78. doi: 10.1074/jbc.M803771200. Epub 2008 Jun 9. J Biol Chem. 2008. PMID: 18541525 Free article.
Peptide antagonists of the PED-hPLD1 binding.
Viparelli F, Doti N, Monti SM, Marasco D, Dathan N, Pedone C, Miele C, Formisano P, Beguinot F, Ruvo M. Viparelli F, et al. Adv Exp Med Biol. 2009;611:445-6. doi: 10.1007/978-0-387-73657-0_192. Adv Exp Med Biol. 2009. PMID: 19400259 No abstract available.
Residues 762-801 of PLD1 mediate the interaction with PED/PEA15.
Doti N, Cassese A, Marasco D, Paturzo F, Sabatella M, Viparelli F, Dathan N, Monti SM, Miele C, Formisano P, Beguinot F, Ruvo M. Doti N, et al. Among authors: viparelli f. Mol Biosyst. 2010 Oct;6(10):2039-48. doi: 10.1039/c005272h. Epub 2010 Aug 11. Mol Biosyst. 2010. PMID: 20714510