Aguirre J - Search Results

1

The yeast Hsp110, Sse1p, exhibits high-affinity peptide binding.

Goeckeler JL, Petruso AP, Aguirre J, Clement CC, Chiosis G, Brodsky JL. Goeckeler JL, et al. Among authors: aguirre j. FEBS Lett. 2008 Jul 9;582(16):2393-6. doi: 10.1016/j.febslet.2008.05.047. Epub 2008 Jun 6. FEBS Lett. 2008. PMID: 18539149 Free PMC article.

2

Design of a fluorescence polarization assay platform for the study of human Hsp70.

Kang Y, Taldone T, Clement CC, Fewell SW, Aguirre J, Brodsky JL, Chiosis G. Kang Y, et al. Among authors: aguirre j. Bioorg Med Chem Lett. 2008 Jul 1;18(13):3749-51. doi: 10.1016/j.bmcl.2008.05.046. Epub 2008 May 16. Bioorg Med Chem Lett. 2008. PMID: 18515098 Free PMC article.

3

Design of a flexible cell-based assay for the evaluation of heat shock protein 70 expression modulators.

Ahn JH, Luo W, Kim J, Rodina A, Clement CC, Aguirre J, Sun W, Kang Y, Maharaj R, Moulick K, Zatorska D, Kokoszka M, Brodsky JL, Chiosis G. Ahn JH, et al. Among authors: aguirre j. Assay Drug Dev Technol. 2011 Jun;9(3):236-46. doi: 10.1089/adt.2010.0327. Epub 2010 Dec 6. Assay Drug Dev Technol. 2011. PMID: 21133677 Free PMC article.

4

Synthesis of a red-shifted fluorescence polarization probe for Hsp90.

Moulick K, Clement CC, Aguirre J, Kim J, Kang Y, Felts S, Chiosis G. Moulick K, et al. Among authors: aguirre j. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4515-8. doi: 10.1016/j.bmcl.2006.06.025. Epub 2006 Jun 22. Bioorg Med Chem Lett. 2006. PMID: 16797988

5

Synthesis of Hsp90 dimerization modulators.

Chiosis G, Aguirre J, Nicchitta CV. Chiosis G, et al. Among authors: aguirre j. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3529-32. doi: 10.1016/j.bmcl.2006.03.092. Epub 2006 Apr 18. Bioorg Med Chem Lett. 2006. PMID: 16621545

6

Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer.

Rodina A, Vilenchik M, Moulick K, Aguirre J, Kim J, Chiang A, Litz J, Clement CC, Kang Y, She Y, Wu N, Felts S, Wipf P, Massague J, Jiang X, Brodsky JL, Krystal GW, Chiosis G. Rodina A, et al. Among authors: aguirre j. Nat Chem Biol. 2007 Aug;3(8):498-507. doi: 10.1038/nchembio.2007.10. Epub 2007 Jul 1. Nat Chem Biol. 2007. PMID: 17603540

7

High-throughput screening fluorescence polarization assay for tumor-specific Hsp90.

Du Y, Moulick K, Rodina A, Aguirre J, Felts S, Dingledine R, Fu H, Chiosis G. Du Y, et al. Among authors: aguirre j. J Biomol Screen. 2007 Oct;12(7):915-24. doi: 10.1177/1087057107306067. J Biomol Screen. 2007. PMID: 17942784

8

Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90.

He H, Zatorska D, Kim J, Aguirre J, Llauger L, She Y, Wu N, Immormino RM, Gewirth DT, Chiosis G. He H, et al. Among authors: aguirre j. J Med Chem. 2006 Jan 12;49(1):381-90. doi: 10.1021/jm0508078. J Med Chem. 2006. PMID: 16392823

9

Evaluation of 8-arylsulfanyl, 8-arylsulfoxyl, and 8-arylsulfonyl adenine derivatives as inhibitors of the heat shock protein 90.

Llauger L, He H, Kim J, Aguirre J, Rosen N, Peters U, Davies P, Chiosis G. Llauger L, et al. Among authors: aguirre j. J Med Chem. 2005 Apr 21;48(8):2892-905. doi: 10.1021/jm049012b. J Med Chem. 2005. PMID: 15828828

10

Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies.

Luo W, Dou F, Rodina A, Chip S, Kim J, Zhao Q, Moulick K, Aguirre J, Wu N, Greengard P, Chiosis G. Luo W, et al. Among authors: aguirre j. Proc Natl Acad Sci U S A. 2007 May 29;104(22):9511-6. doi: 10.1073/pnas.0701055104. Epub 2007 May 21. Proc Natl Acad Sci U S A. 2007. PMID: 17517623 Free PMC article.

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