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A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice.
Savage DB, Zhai L, Ravikumar B, Choi CS, Snaar JE, McGuire AC, Wou SE, Medina-Gomez G, Kim S, Bock CB, Segvich DM, Solanky B, Deelchand D, Vidal-Puig A, Wareham NJ, Shulman GI, Karpe F, Taylor R, Pederson BA, Roach PJ, O'Rahilly S, DePaoli-Roach AA. Savage DB, et al. Among authors: ravikumar b. PLoS Med. 2008 Jan 29;5(1):e27. doi: 10.1371/journal.pmed.0050027. PLoS Med. 2008. PMID: 18232732 Free PMC article.
Broad proteomics analysis of seeding-induced aggregation of α-synuclein in M83 neurons reveals remodeling of proteostasis mechanisms that might contribute to Parkinson's disease pathogenesis.
Lumpkin CJ, Patel H, Potts GK, Chaurasia S, Gibilisco L, Srivastava GP, Lee JY, Brown NJ, Amarante P, Williams JD, Karran E, Townsend M, Woods D, Ravikumar B. Lumpkin CJ, et al. Among authors: ravikumar b. Mol Brain. 2024 May 22;17(1):26. doi: 10.1186/s13041-024-01099-1. Mol Brain. 2024. PMID: 38778381 Free PMC article.
Drug-induced liver injury in children.
Ravikumar B, Aithal G, Kelgeri C. Ravikumar B, et al. Arch Dis Child Educ Pract Ed. 2024 May 15:edpract-2024-326853. doi: 10.1136/archdischild-2024-326853. Online ahead of print. Arch Dis Child Educ Pract Ed. 2024. PMID: 38749665 No abstract available.
Establishment of a high-content imaging assay for tau aggregation in hiPSC-derived neurons differentiated from two protocols to routinely evaluate compounds and genetic perturbations.
Bahnassawy L, Nicolaisen N, Untucht C, Mielich-Süss B, Reinhardt L, Ried JS, Morawe MP, Geist D, Finck A, Käfer E, Korffmann J, Townsend M, Ravikumar B, Lakics V, Cik M, Reinhardt P. Bahnassawy L, et al. Among authors: ravikumar b. SLAS Discov. 2024 Mar;29(2):100137. doi: 10.1016/j.slasd.2023.12.009. Epub 2023 Dec 19. SLAS Discov. 2024. PMID: 38128829 Free article.
110 results