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Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene.
Montero-Conde C, Leandro-Garcia LJ, Chen X, Oler G, Ruiz-Llorente S, Ryder M, Landa I, Sanchez-Vega F, La K, Ghossein RA, Bajorin DF, Knauf JA, Riordan JD, Dupuy AJ, Fagin JA. Montero-Conde C, et al. Among authors: chen x. Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):E4951-E4960. doi: 10.1073/pnas.1702723114. Epub 2017 Jun 5. Proc Natl Acad Sci U S A. 2017. PMID: 28584132 Free PMC article.
Cholesterol depletion from the plasma membrane triggers ligand-independent activation of the epidermal growth factor receptor.
Chen X, Resh MD. Chen X, et al. J Biol Chem. 2002 Dec 20;277(51):49631-7. doi: 10.1074/jbc.M208327200. Epub 2002 Oct 22. J Biol Chem. 2002. PMID: 12397069 Free article.
We recently demonstrated that depletion of plasma membrane cholesterol with methyl-beta-cyclodextrin (MbetaCD) caused activation of MAPK (Chen, X., and Resh, M. D. (2001) J. Biol. Chem. 276, 34617-34623). MAPK activation was phosphatidylinositol 3-kinase (PI3K)-depe …
We recently demonstrated that depletion of plasma membrane cholesterol with methyl-beta-cyclodextrin (MbetaCD) caused activation of MAPK ( …
Three-dimensional genome architecture in intrahepatic cholangiocarcinoma.
Liang Y, Li C, Zou R, Ying L, Chen X, Wang Z, Zhang W, Hao M, Yang H, Guo R, Lei G, Sun F, Zhao K, Zhang Y, Dai J, Feng S, Zhang K, Guo L, Liu S, Wan C, Wang L, Yang P, Yang Z. Liang Y, et al. Among authors: chen x. Cell Oncol (Dordr). 2025 Jan 20. doi: 10.1007/s13402-024-01033-6. Online ahead of print. Cell Oncol (Dordr). 2025. PMID: 39831920
118,074 results
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