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Page 1
Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma.
Plentz R, Park JS, Rhim AD, Abravanel D, Hezel AF, Sharma SV, Gurumurthy S, Deshpande V, Kenific C, Settleman J, Majumder PK, Stanger BZ, Bardeesy N. Plentz R, et al. Among authors: bardeesy n. Gastroenterology. 2009 May;136(5):1741-9.e6. doi: 10.1053/j.gastro.2009.01.008. Epub 2009 Jan 14. Gastroenterology. 2009. PMID: 19208345 Free PMC article.
Combined MEK and PI3K inhibition in a mouse model of pancreatic cancer.
Alagesan B, Contino G, Guimaraes AR, Corcoran RB, Deshpande V, Wojtkiewicz GR, Hezel AF, Wong KK, Loda M, Weissleder R, Benes CH, Engelman J, Bardeesy N. Alagesan B, et al. Among authors: bardeesy n. Clin Cancer Res. 2015 Jan 15;21(2):396-404. doi: 10.1158/1078-0432.CCR-14-1591. Epub 2014 Oct 27. Clin Cancer Res. 2015. PMID: 25348516 Free PMC article.
Stromal response to Hedgehog signaling restrains pancreatic cancer progression.
Lee JJ, Perera RM, Wang H, Wu DC, Liu XS, Han S, Fitamant J, Jones PD, Ghanta KS, Kawano S, Nagle JM, Deshpande V, Boucher Y, Kato T, Chen JK, Willmann JK, Bardeesy N, Beachy PA. Lee JJ, et al. Among authors: bardeesy n. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):E3091-100. doi: 10.1073/pnas.1411679111. Epub 2014 Jul 14. Proc Natl Acad Sci U S A. 2014. PMID: 25024225 Free PMC article.
Tumor engraftment in patient-derived xenografts of pancreatic ductal adenocarcinoma is associated with adverse clinicopathological features and poor survival.
Pergolini I, Morales-Oyarvide V, Mino-Kenudson M, Honselmann KC, Rosenbaum MW, Nahar S, Kem M, Ferrone CR, Lillemoe KD, Bardeesy N, Ryan DP, Thayer SP, Warshaw AL, Fernández-Del Castillo C, Liss AS. Pergolini I, et al. Among authors: bardeesy n. PLoS One. 2017 Aug 30;12(8):e0182855. doi: 10.1371/journal.pone.0182855. eCollection 2017. PLoS One. 2017. PMID: 28854237 Free PMC article.
Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma.
Aoki S, Inoue K, Klein S, Halvorsen S, Chen J, Matsui A, Nikmaneshi MR, Kitahara S, Hato T, Chen X, Kawakubo K, Nia HT, Chen I, Schanne DH, Mamessier E, Shigeta K, Kikuchi H, Ramjiawan RR, Schmidt TC, Iwasaki M, Yau T, Hong TS, Quaas A, Plum PS, Dima S, Popescu I, Bardeesy N, Munn LL, Borad MJ, Sassi S, Jain RK, Zhu AX, Duda DG. Aoki S, et al. Among authors: bardeesy n. Gut. 2022 Jan;71(1):185-193. doi: 10.1136/gutjnl-2020-322493. Epub 2021 Jan 11. Gut. 2022. PMID: 33431577 Free PMC article.
Genetics and biology of pancreatic ductal adenocarcinoma.
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA. Hezel AF, et al. Among authors: bardeesy n. Genes Dev. 2006 May 15;20(10):1218-49. doi: 10.1101/gad.1415606. Genes Dev. 2006. PMID: 16702400 Free article. Review.
Hedgehog promotes neovascularization in pancreatic cancers by regulating Ang-1 and IGF-1 expression in bone-marrow derived pro-angiogenic cells.
Nakamura K, Sasajima J, Mizukami Y, Sugiyama Y, Yamazaki M, Fujii R, Kawamoto T, Koizumi K, Sato K, Fujiya M, Sasaki K, Tanno S, Okumura T, Shimizu N, Kawabe J, Karasaki H, Kono T, Ii M, Bardeesy N, Chung DC, Kohgo Y. Nakamura K, et al. Among authors: bardeesy n. PLoS One. 2010 Jan 21;5(1):e8824. doi: 10.1371/journal.pone.0008824. PLoS One. 2010. PMID: 20098680 Free PMC article.
240 results