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Bypassing a kinase activity with an ATP-competitive drug.
Papa FR, Zhang C, Shokat K, Walter P. Papa FR, et al. Among authors: zhang c. Science. 2003 Nov 28;302(5650):1533-7. doi: 10.1126/science.1090031. Epub 2003 Oct 16. Science. 2003. PMID: 14564015
The unfolded protein response signals through high-order assembly of Ire1.
Korennykh AV, Egea PF, Korostelev AA, Finer-Moore J, Zhang C, Shokat KM, Stroud RM, Walter P. Korennykh AV, et al. Among authors: zhang c. Nature. 2009 Feb 5;457(7230):687-93. doi: 10.1038/nature07661. Epub 2008 Dec 14. Nature. 2009. PMID: 19079236 Free PMC article.
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