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Multiple-dose pharmacokinetics, pharmacodynamics, and safety of taranabant, a novel selective cannabinoid-1 receptor inverse agonist, in healthy male volunteers.
Addy C, Rothenberg P, Li S, Majumdar A, Agrawal N, Li H, Zhong L, Yuan J, Maes A, Dunbar S, Cote J, Rosko K, Van Dyck K, De Lepeleire I, de Hoon J, Van Hecken A, Depré M, Knops A, Gottesdiener K, Stoch A, Wagner J. Addy C, et al. Among authors: de lepeleire i, de hoon j. J Clin Pharmacol. 2008 Jun;48(6):734-44. doi: 10.1177/0091270008317591. J Clin Pharmacol. 2008. PMID: 18508950 Clinical Trial.
Effects of enteric-coated, low-dose aspirin on parameters of platelet function.
Van Hecken A, Juliano ML, Depré M, De Lepeleire I, Arnout J, Dynder A, Wildonger L, Petty KJ, Gottesdiener K, De Hoon JN. Van Hecken A, et al. Among authors: de lepeleire i, de hoon jn. Aliment Pharmacol Ther. 2002 Sep;16(9):1683-8. doi: 10.1046/j.1365-2036.2002.01332.x. Aliment Pharmacol Ther. 2002. PMID: 12197849 Clinical Trial.
Effect of aprepitant on the pharmacokinetics and pharmacodynamics of warfarin.
Depré M, Van Hecken A, Oeyen M, De Lepeleire I, Laethem T, Rothenberg P, Petty KJ, Majumdar A, Crumley T, Panebianco D, Bergman A, de Hoon JN. Depré M, et al. Among authors: de lepeleire i, de hoon jn. Eur J Clin Pharmacol. 2005 Jul;61(5-6):341-6. doi: 10.1007/s00228-005-0907-8. Epub 2005 Jun 28. Eur J Clin Pharmacol. 2005. PMID: 15983826 Clinical Trial.
The effect of MK-0524, a prostaglandin D(2) receptor antagonist, on prostaglandin D (2)-induced nasal airway obstruction in healthy volunteers.
Van Hecken A, Depré M, De Lepeleire I, Thach C, Oeyen M, Van Effen J, Laethem T, Mazina K, Crumley T, Wenning L, Gottesdiener KM, Deutsch P, Clement P, Lai E, de Hoon JN. Van Hecken A, et al. Among authors: de lepeleire i, de hoon jn. Eur J Clin Pharmacol. 2007 Feb;63(2):135-41. doi: 10.1007/s00228-006-0211-2. Epub 2007 Jan 3. Eur J Clin Pharmacol. 2007. PMID: 17200838 Clinical Trial.
[18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor.
Burns HD, Van Laere K, Sanabria-Bohórquez S, Hamill TG, Bormans G, Eng WS, Gibson R, Ryan C, Connolly B, Patel S, Krause S, Vanko A, Van Hecken A, Dupont P, De Lepeleire I, Rothenberg P, Stoch SA, Cote J, Hagmann WK, Jewell JP, Lin LS, Liu P, Goulet MT, Gottesdiener K, Wagner JA, de Hoon J, Mortelmans L, Fong TM, Hargreaves RJ. Burns HD, et al. Among authors: de lepeleire i, de hoon j. Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9800-5. doi: 10.1073/pnas.0703472104. Epub 2007 May 29. Proc Natl Acad Sci U S A. 2007. PMID: 17535893 Free PMC article.
184 results