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Page 1
IRAK-4 inhibitors. Part III: a series of imidazo[1,2-a]pyridines.
Buckley GM, Fosbeary R, Fraser JL, Gowers L, Higueruelo AP, James LA, Jenkins K, Mack SR, Morgan T, Parry DM, Pitt WR, Rausch O, Richard MD, Sabin V. Buckley GM, et al. Among authors: rausch o. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3656-60. doi: 10.1016/j.bmcl.2008.04.042. Epub 2008 Apr 24. Bioorg Med Chem Lett. 2008. PMID: 18501603
IRAK-4 inhibitors. Part 1: a series of amides.
Buckley GM, Gowers L, Higueruelo AP, Jenkins K, Mack SR, Morgan T, Parry DM, Pitt WR, Rausch O, Richard MD, Sabin V, Fraser JL. Buckley GM, et al. Among authors: rausch o. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3211-4. doi: 10.1016/j.bmcl.2008.04.058. Epub 2008 Apr 26. Bioorg Med Chem Lett. 2008. PMID: 18474425
IRAK-4 inhibitors. Part II: a structure-based assessment of imidazo[1,2-a]pyridine binding.
Buckley GM, Ceska TA, Fraser JL, Gowers L, Groom CR, Higueruelo AP, Jenkins K, Mack SR, Morgan T, Parry DM, Pitt WR, Rausch O, Richard MD, Sabin V. Buckley GM, et al. Among authors: rausch o. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3291-5. doi: 10.1016/j.bmcl.2008.04.039. Epub 2008 Apr 22. Bioorg Med Chem Lett. 2008. PMID: 18482836
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.
Yankova E, Blackaby W, Albertella M, Rak J, De Braekeleer E, Tsagkogeorga G, Pilka ES, Aspris D, Leggate D, Hendrick AG, Webster NA, Andrews B, Fosbeary R, Guest P, Irigoyen N, Eleftheriou M, Gozdecka M, Dias JML, Bannister AJ, Vick B, Jeremias I, Vassiliou GS, Rausch O, Tzelepis K, Kouzarides T. Yankova E, et al. Among authors: rausch o. Nature. 2021 May;593(7860):597-601. doi: 10.1038/s41586-021-03536-w. Epub 2021 Apr 26. Nature. 2021. PMID: 33902106 Free PMC article.
High content cellular screening.
Rausch O. Rausch O. Curr Opin Chem Biol. 2006 Aug;10(4):316-20. doi: 10.1016/j.cbpa.2006.06.004. Epub 2006 Jun 21. Curr Opin Chem Biol. 2006. PMID: 16793326 Review.
RNA-modifying enzymes and their function in a chromatin context.
Tzelepis K, Rausch O, Kouzarides T. Tzelepis K, et al. Among authors: rausch o. Nat Struct Mol Biol. 2019 Oct;26(10):858-862. doi: 10.1038/s41594-019-0312-0. Epub 2019 Oct 3. Nat Struct Mol Biol. 2019. PMID: 31582848 Free PMC article. Review.
Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning.
Körtel N, Rücklé C, Zhou Y, Busch A, Hoch-Kraft P, Sutandy FXR, Haase J, Pradhan M, Musheev M, Ostareck D, Ostareck-Lederer A, Dieterich C, Hüttelmaier S, Niehrs C, Rausch O, Dominissini D, König J, Zarnack K. Körtel N, et al. Among authors: rausch o. Nucleic Acids Res. 2021 Sep 20;49(16):e92. doi: 10.1093/nar/gkab485. Nucleic Acids Res. 2021. PMID: 34157120 Free PMC article.
29 results