Cohen-Williams ME - Search Results

1

The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510).

Varty GB, Lu SX, Morgan CA, Cohen-Williams ME, Hodgson RA, Smith-Torhan A, Zhang H, Fawzi AB, Graziano MP, Ho GD, Matasi J, Tulshian D, Coffin VL, Carey GJ. Varty GB, et al. Among authors: cohen williams me. J Pharmacol Exp Ther. 2008 Aug;326(2):672-82. doi: 10.1124/jpet.108.136937. Epub 2008 May 20. J Pharmacol Exp Ther. 2008. PMID: 18492950

2

The gerbil elevated plus-maze II: anxiolytic-like effects of selective neurokinin NK1 receptor antagonists.

Varty GB, Cohen-Williams ME, Morgan CA, Pylak U, Duffy RA, Lachowicz JE, Carey GJ, Coffin VL. Varty GB, et al. Neuropsychopharmacology. 2002 Sep;27(3):371-9. doi: 10.1016/S0893-133X(02)00313-5. Neuropsychopharmacology. 2002. PMID: 12225694

3

Characterization of the potent and highly selective A2A receptor antagonists preladenant and SCH 412348 [7-[2-[4-2,4-difluorophenyl]-1-piperazinyl]ethyl]-2-(2-furanyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine] in rodent models of movement disorders and depression.

Hodgson RA, Bertorelli R, Varty GB, Lachowicz JE, Forlani A, Fredduzzi S, Cohen-Williams ME, Higgins GA, Impagnatiello F, Nicolussi E, Parra LE, Foster C, Zhai Y, Neustadt BR, Stamford AW, Parker EM, Reggiani A, Hunter JC. Hodgson RA, et al. Among authors: cohen williams me. J Pharmacol Exp Ther. 2009 Jul;330(1):294-303. doi: 10.1124/jpet.108.149617. Epub 2009 Mar 30. J Pharmacol Exp Ther. 2009. PMID: 19332567

4

The antidepressant-like effects of neurokinin NK1 receptor antagonists in a gerbil tail suspension test.

Varty GB, Cohen-Williams ME, Hunter JC. Varty GB, et al. Behav Pharmacol. 2003 Feb;14(1):87-95. doi: 10.1097/00008877-200302000-00009. Behav Pharmacol. 2003. PMID: 12576885

5

Centrally administered hemokinin-1 (HK-1), a neurokinin NK1 receptor agonist, produces substance P-like behavioral effects in mice and gerbils.

Duffy RA, Hedrick JA, Randolph G, Morgan CA, Cohen-Williams ME, Vassileva G, Lachowicz JE, Laverty M, Maguire M, Shan LS, Gustafson E, Varty GB. Duffy RA, et al. Neuropharmacology. 2003 Aug;45(2):242-50. doi: 10.1016/s0028-3908(03)00150-3. Neuropharmacology. 2003. PMID: 12842130

6

The gerbil elevated plus-maze I: behavioral characterization and pharmacological validation.

Varty GB, Morgan CA, Cohen-Williams ME, Coffin VL, Carey GJ. Varty GB, et al. Neuropsychopharmacology. 2002 Sep;27(3):357-70. doi: 10.1016/S0893-133X(02)00312-3. Neuropsychopharmacology. 2002. PMID: 12225693

7

2-(2-Furanyl)-7-phenyl[1,2,4]triazolo[1,5-c]pyrimidin-5-amine analogs: highly potent, orally active, adenosine A2A antagonists. Part 1.

Matasi JJ, Caldwell JP, Zhang H, Fawzi A, Cohen-Williams ME, Varty GB, Tulshian DB. Matasi JJ, et al. Bioorg Med Chem Lett. 2005 Aug 15;15(16):3670-4. doi: 10.1016/j.bmcl.2005.05.086. Bioorg Med Chem Lett. 2005. PMID: 15978806

8

2-(2-Furanyl)-7-phenyl[1,2,4]triazolo[1,5-c]pyrimidin-5-amine analogs as adenosine A2A antagonists: the successful reduction of hERG activity. Part 2.

Matasi JJ, Caldwell JP, Zhang H, Fawzi A, Higgins GA, Cohen-Williams ME, Varty GB, Tulshian DB. Matasi JJ, et al. Among authors: cohen williams me. Bioorg Med Chem Lett. 2005 Aug 15;15(16):3675-8. doi: 10.1016/j.bmcl.2005.05.043. Bioorg Med Chem Lett. 2005. PMID: 15982882

9

The effect of caffeine to increase reaction time in the rat during a test of attention is mediated through antagonism of adenosine A2A receptors.

Higgins GA, Grzelak ME, Pond AJ, Cohen-Williams ME, Hodgson RA, Varty GB. Higgins GA, et al. Among authors: cohen williams me. Behav Brain Res. 2007 Dec 11;185(1):32-42. doi: 10.1016/j.bbr.2007.07.013. Epub 2007 Jul 17. Behav Brain Res. 2007. PMID: 17707919

10

Characterization of the selective mGluR1 antagonist, JNJ16259685, in rodent models of movement and coordination.

Hodgson RA, Hyde LA, Guthrie DH, Cohen-Williams ME, Leach PT, Kazdoba TM, Bleickardt CJ, Lu SX, Parker EM, Varty GB. Hodgson RA, et al. Among authors: cohen williams me. Pharmacol Biochem Behav. 2011 Apr;98(2):181-7. doi: 10.1016/j.pbb.2010.11.018. Epub 2010 Nov 28. Pharmacol Biochem Behav. 2011. PMID: 21122808

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