You Q - Search Results

1

Competitive or noncompetitive, that's the question: research toward histone deacetylase inhibitors.

Su H, Altucci L, You Q. Su H, et al. Among authors: you q. Mol Cancer Ther. 2008 May;7(5):1007-12. doi: 10.1158/1535-7163.MCT-07-2289. Mol Cancer Ther. 2008. PMID: 18483291 Review.

2

Identification of ligand features essential for HDACs inhibitors by pharmacophore modeling.

Chen YD, Jiang YJ, Zhou JW, Yu QS, You QD. Chen YD, et al. J Mol Graph Model. 2008 Apr;26(7):1160-8. doi: 10.1016/j.jmgm.2007.10.007. Epub 2007 Oct 23. J Mol Graph Model. 2008. PMID: 18061500

3

Design, synthesis and biological evaluation of novel compounds with conjugated structure as anti-tumor agents.

Su H, Nebbioso A, Carafa V, Chen Y, Yang B, Altucci L, You Q. Su H, et al. Among authors: you q. Bioorg Med Chem. 2008 Sep 1;16(17):7992-8002. doi: 10.1016/j.bmc.2008.07.066. Epub 2008 Jul 29. Bioorg Med Chem. 2008. PMID: 18701301

4

Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells.

Gu H, Wang X, Rao S, Wang J, Zhao J, Ren FL, Mu R, Yang Y, Qi Q, Liu W, Lu N, Ling H, You Q, Guo Q. Gu H, et al. Among authors: you q. Mol Cancer Ther. 2008 Oct;7(10):3298-305. doi: 10.1158/1535-7163.MCT-08-0212. Mol Cancer Ther. 2008. PMID: 18852133

5

3D-QSAR studies of HDACs inhibitors using pharmacophore-based alignment.

Chen Y, Li H, Tang W, Zhu C, Jiang Y, Zou J, Yu Q, You Q. Chen Y, et al. Among authors: you q. Eur J Med Chem. 2009 Jul;44(7):2868-76. doi: 10.1016/j.ejmech.2008.12.008. Epub 2008 Dec 16. Eur J Med Chem. 2009. PMID: 19136179

6

Novel N-hydroxybenzamide-based HDAC inhibitors with branched CAP group.

Su H, Yu L, Nebbioso A, Carafa V, Chen Y, Altucci L, You Q. Su H, et al. Among authors: you q. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6284-8. doi: 10.1016/j.bmcl.2009.09.100. Epub 2009 Sep 29. Bioorg Med Chem Lett. 2009. PMID: 19822426

7

[Design, synthesis, and biological activities of histone deacetylase inhibitors with diketo ester as zinc binding group].

Lu H, Su H, Yang B, You QD. Lu H, et al. Yao Xue Xue Bao. 2011 Mar;46(3):293-8. Yao Xue Xue Bao. 2011. PMID: 21626783 Chinese.

8

Novel N-hydroxyfurylacrylamide-based histone deacetylase (HDAC) inhibitors with branched CAP group (Part 2).

Feng T, Wang H, Su H, Lu H, Yu L, Zhang X, Sun H, You Q. Feng T, et al. Among authors: you q. Bioorg Med Chem. 2013 Sep 1;21(17):5339-54. doi: 10.1016/j.bmc.2013.06.009. Epub 2013 Jun 15. Bioorg Med Chem. 2013. PMID: 23820574

9

G9a - An Appealing Antineoplastic Target.

Chen WL, Sun HP, Li DD, Wang ZH, You QD, Guo XK. Chen WL, et al. Curr Cancer Drug Targets. 2017;17(6):555-568. doi: 10.2174/1568009616666160512145303. Curr Cancer Drug Targets. 2017. PMID: 27174055 Review.

10

Docking studies on kinesin spindle protein inhibitors: an important cooperative 'minor binding pocket' which increases the binding affinity significantly.

Jiang C, Chen Y, Wang X, You Q. Jiang C, et al. Among authors: you q. J Mol Model. 2007 Sep;13(9):987-92. doi: 10.1007/s00894-007-0219-2. Epub 2007 Jun 23. J Mol Model. 2007. PMID: 17588180

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