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Hepatocyte-specific Epidermal Growth Factor Receptor Deletion Promotes Fibrosis but has no Effect on Steatosis in Fast-food Diet Model of Metabolic Dysfunction-associated Steatotic Liver Disease.
Bano S, Copeland MA, Stoops JW, Orr A, Jain S, Paranjpe S, Mooli RGR, Ramakrishnan SK, Locker J, Mars WM, Michalopoulos GK, Bhushan B. Bano S, et al. Among authors: locker j. Cell Mol Gastroenterol Hepatol. 2024;18(4):101380. doi: 10.1016/j.jcmgh.2024.101380. Epub 2024 Jul 20. Cell Mol Gastroenterol Hepatol. 2024. PMID: 39038606 Free PMC article.
TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution.
Qu B, Miskey C, Gömer A, Kleinert RDV, Ibanez SC, Eberle R, Ebenig A, Postmus D, Nocke MK, Herrmann M, Itotia TK, Herrmann ST, Heinen N, Höck S, Hastert FD, von Rhein C, Schürmann C, Li X, van Zandbergen G, Widera M, Ciesek S, Schnierle BS, Tarr AW, Steinmann E, Goffinet C, Pfaender S, Locker JK, Mühlebach MD, Todt D, Brown RJP. Qu B, et al. Among authors: locker jk. Proc Natl Acad Sci U S A. 2024 Jun 4;121(23):e2407437121. doi: 10.1073/pnas.2407437121. Epub 2024 May 30. Proc Natl Acad Sci U S A. 2024. PMID: 38814864 Free PMC article.
The palisade layer of the poxvirus core is composed of flexible A10 trimers.
Liu J, Corroyer-Dulmont S, Pražák V, Khusainov I, Bahrami K, Welsch S, Vasishtan D, Obarska-Kosińska A, Thorkelsson SR, Grünewald K, Quemin ERJ, Turoňová B, Locker JK. Liu J, et al. Among authors: locker jk. Nat Struct Mol Biol. 2024 Jul;31(7):1105-1113. doi: 10.1038/s41594-024-01218-5. Epub 2024 Feb 5. Nat Struct Mol Biol. 2024. PMID: 38316878 Free PMC article.
Hepatocyte Smoothened Activity Controls Susceptibility to Insulin Resistance and Nonalcoholic Fatty Liver Disease.
Chen T, Dalton G, Oh SH, Maeso-Diaz R, Du K, Meyers RA, Guy C, Abdelmalek MF, Henao R, Guarnieri P, Pullen SS, Gregory S, Locker J, Brown JM, Diehl AM. Chen T, et al. Among authors: locker j. Cell Mol Gastroenterol Hepatol. 2023;15(4):949-970. doi: 10.1016/j.jcmgh.2022.12.008. Epub 2022 Dec 16. Cell Mol Gastroenterol Hepatol. 2023. PMID: 36535507 Free PMC article.
222 results