Watson IA - Search Results

1

Quantitative measurement of monoclonal antibody distribution and blood flow using positron emission tomography and 124iodine in patients with breast cancer.

Wilson CB, Snook DE, Dhokia B, Taylor CV, Watson IA, Lammertsma AA, Lambrecht R, Waxman J, Jones T, Epenetos AA. Wilson CB, et al. Among authors: watson ia. Int J Cancer. 1991 Feb 1;47(3):344-7. doi: 10.1002/ijc.2910470305. Int J Cancer. 1991. PMID: 1847121

2

The potential of high-resolution positron emission tomography to monitor striatal dopaminergic function in rat models of disease.

Hume SP, Lammertsma AA, Myers R, Rajeswaran S, Bloomfield PM, Ashworth S, Fricker RA, Torres EM, Watson I, Jones T. Hume SP, et al. J Neurosci Methods. 1996 Aug;67(2):103-12. J Neurosci Methods. 1996. PMID: 8872875

3

Use of short- and long-lived rubidium tracers for the study of transient ischemia.

Shea MJ, Wilson RA, deLandsheere CM, Deanfield JE, Watson IA, Kensett MJ, Jones T, Selwyn AP. Shea MJ, et al. Among authors: watson ia. J Nucl Med. 1987 Jun;28(6):989-97. J Nucl Med. 1987. PMID: 3495648 Free article.

4

Quantitative in vivo measurements of tumor perfusion using rubidium-81 and positron emission tomography.

Cherry SR, Carnochan P, Babich JW, Serafini F, Rowell NP, Watson IA. Cherry SR, et al. Among authors: watson ia. J Nucl Med. 1990 Aug;31(8):1307-15. J Nucl Med. 1990. PMID: 2384797 Free article.

5

QSAR Model of Unbound Brain-to-Plasma Partition Coefficient, K_p,uu,brain: Incorporating P-glycoprotein Efflux as a Variable.

Dolgikh E, Watson IA, Desai PV, Sawada GA, Morton S, Jones TM, Raub TJ. Dolgikh E, et al. Among authors: watson ia. J Chem Inf Model. 2016 Nov 28;56(11):2225-2233. doi: 10.1021/acs.jcim.6b00229. Epub 2016 Oct 13. J Chem Inf Model. 2016. PMID: 27684523

6

Integration of in silico and in vitro tools for scaffold optimization during drug discovery: predicting P-glycoprotein efflux.

Desai PV, Sawada GA, Watson IA, Raub TJ. Desai PV, et al. Among authors: watson ia. Mol Pharm. 2013 Apr 1;10(4):1249-61. doi: 10.1021/mp300555n. Epub 2013 Mar 1. Mol Pharm. 2013. PMID: 23363443

7

High-throughput hydrogen bond strength calculation and its applications in optimizing drug ADME properties.

Shen J, Yang Y, Broughton H, Watson IA, Desai PV. Shen J, et al. Among authors: watson ia. Future Med Chem. 2019 Mar;11(6):511-524. doi: 10.4155/fmc-2018-0470. Epub 2019 Mar 20. Future Med Chem. 2019. PMID: 30892942

8

The Proximal Lilly Collection: Mapping, Exploring and Exploiting Feasible Chemical Space.

Nicolaou CA, Watson IA, Hu H, Wang J. Nicolaou CA, et al. Among authors: watson ia. J Chem Inf Model. 2016 Jul 25;56(7):1253-66. doi: 10.1021/acs.jcim.6b00173. Epub 2016 Jun 27. J Chem Inf Model. 2016. PMID: 27286472

9

Rationalizing lead optimization by associating quantitative relevance with molecular structure modification.

Raymond JW, Watson IA, Mahoui A. Raymond JW, et al. Among authors: watson ia. J Chem Inf Model. 2009 Aug;49(8):1952-62. doi: 10.1021/ci9000426. J Chem Inf Model. 2009. PMID: 19603805

10

Indirect similarity based methods for effective scaffold-hopping in chemical compounds.

Wale N, Watson IA, Karypis G. Wale N, et al. Among authors: watson ia. J Chem Inf Model. 2008 Apr;48(4):730-41. doi: 10.1021/ci700369e. Epub 2008 Apr 11. J Chem Inf Model. 2008. PMID: 18402435 Free PMC article.

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