Zakikhani M - Search Results

1

Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth.

Algire C, Zakikhani M, Blouin MJ, Shuai JH, Pollak M. Algire C, et al. Among authors: zakikhani m. Endocr Relat Cancer. 2008 Sep;15(3):833-9. doi: 10.1677/ERC-08-0038. Epub 2008 May 9. Endocr Relat Cancer. 2008. PMID: 18469156

2

Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo.

Algire C, Amrein L, Bazile M, David S, Zakikhani M, Pollak M. Algire C, et al. Among authors: zakikhani m. Oncogene. 2011 Mar 10;30(10):1174-82. doi: 10.1038/onc.2010.483. Epub 2010 Nov 22. Oncogene. 2011. PMID: 21102522

3

Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells.

Zakikhani M, Dowling R, Fantus IG, Sonenberg N, Pollak M. Zakikhani M, et al. Cancer Res. 2006 Nov 1;66(21):10269-73. doi: 10.1158/0008-5472.CAN-06-1500. Epub 2006 Oct 23. Cancer Res. 2006. PMID: 17062558

4

Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells.

Zakikhani M, Blouin MJ, Piura E, Pollak MN. Zakikhani M, et al. Breast Cancer Res Treat. 2010 Aug;123(1):271-9. doi: 10.1007/s10549-010-0763-9. Epub 2010 Feb 5. Breast Cancer Res Treat. 2010. PMID: 20135346

5

Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase.

Algire C, Amrein L, Zakikhani M, Panasci L, Pollak M. Algire C, et al. Among authors: zakikhani m. Endocr Relat Cancer. 2010 Jun 1;17(2):351-60. doi: 10.1677/ERC-09-0252. Print 2010 Jun. Endocr Relat Cancer. 2010. PMID: 20228137

6

Effects of castration on insulin levels and glucose tolerance in the mouse differ from those in man.

Inoue T, Zakikhani M, David S, Algire C, Blouin MJ, Pollak M. Inoue T, et al. Among authors: zakikhani m. Prostate. 2010 Nov 1;70(15):1628-35. doi: 10.1002/pros.21198. Prostate. 2010. PMID: 20564323

7

Metformin abolishes increased tumor (18)F-2-fluoro-2-deoxy-D-glucose uptake associated with a high energy diet.

Mashhedi H, Blouin MJ, Zakikhani M, David S, Zhao Y, Bazile M, Birman E, Algire C, Aliaga A, Bedell BJ, Pollak M. Mashhedi H, et al. Among authors: zakikhani m. Cell Cycle. 2011 Aug 15;10(16):2770-8. doi: 10.4161/cc.10.16.16219. Epub 2011 Aug 15. Cell Cycle. 2011. PMID: 21811094

8

IGF1/insulin receptor kinase inhibition by BMS-536924 is better tolerated than alloxan-induced hypoinsulinemia and more effective than metformin in the treatment of experimental insulin-responsive breast cancer.

Dool CJ, Mashhedi H, Zakikhani M, David S, Zhao Y, Birman E, Carboni JM, Gottardis M, Blouin MJ, Pollak M. Dool CJ, et al. Among authors: zakikhani m. Endocr Relat Cancer. 2011 Nov 14;18(6):699-709. doi: 10.1530/ERC-11-0136. Print 2011 Dec. Endocr Relat Cancer. 2011. PMID: 21946410

9

Carbon source and myc expression influence the antiproliferative actions of metformin.

Javeshghani S, Zakikhani M, Austin S, Bazile M, Blouin MJ, Topisirovic I, St-Pierre J, Pollak MN. Javeshghani S, et al. Among authors: zakikhani m. Cancer Res. 2012 Dec 1;72(23):6257-67. doi: 10.1158/0008-5472.CAN-12-2907. Epub 2012 Oct 4. Cancer Res. 2012. PMID: 23041548

10

Serine deprivation enhances antineoplastic activity of biguanides.

Gravel SP, Hulea L, Toban N, Birman E, Blouin MJ, Zakikhani M, Zhao Y, Topisirovic I, St-Pierre J, Pollak M. Gravel SP, et al. Among authors: zakikhani m. Cancer Res. 2014 Dec 15;74(24):7521-33. doi: 10.1158/0008-5472.CAN-14-2643-T. Epub 2014 Nov 6. Cancer Res. 2014. PMID: 25377470

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