Yap TL - Search Results

1

Mutagenesis of the dengue virus type 2 NS5 methyltransferase domain.

Kroschewski H, Lim SP, Butcher RE, Yap TL, Lescar J, Wright PJ, Vasudevan SG, Davidson AD. Kroschewski H, et al. Among authors: yap tl. J Biol Chem. 2008 Jul 11;283(28):19410-21. doi: 10.1074/jbc.M800613200. Epub 2008 May 9. J Biol Chem. 2008. PMID: 18469001 Free article.

2

A multi-step strategy to obtain crystals of the dengue virus RNA-dependent RNA polymerase that diffract to high resolution.

Yap TL, Chen YL, Xu T, Wen D, Vasudevan SG, Lescar J. Yap TL, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Feb 1;63(Pt 2):78-83. doi: 10.1107/S1744309106055084. Epub 2007 Jan 17. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 17277444 Free PMC article.

3

Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-angstrom resolution.

Yap TL, Xu T, Chen YL, Malet H, Egloff MP, Canard B, Vasudevan SG, Lescar J. Yap TL, et al. J Virol. 2007 May;81(9):4753-65. doi: 10.1128/JVI.02283-06. Epub 2007 Feb 14. J Virol. 2007. PMID: 17301146 Free PMC article.

4

A scintillation proximity assay for dengue virus NS5 2'-O-methyltransferase-kinetic and inhibition analyses.

Lim SP, Wen D, Yap TL, Yan CK, Lescar J, Vasudevan SG. Lim SP, et al. Among authors: yap tl. Antiviral Res. 2008 Dec;80(3):360-9. doi: 10.1016/j.antiviral.2008.08.005. Epub 2008 Sep 20. Antiviral Res. 2008. PMID: 18809436

5

The flavivirus polymerase as a target for drug discovery.

Malet H, Massé N, Selisko B, Romette JL, Alvarez K, Guillemot JC, Tolou H, Yap TL, Vasudevan S, Lescar J, Canard B. Malet H, et al. Among authors: yap tl. Antiviral Res. 2008 Oct;80(1):23-35. doi: 10.1016/j.antiviral.2008.06.007. Epub 2008 Jul 9. Antiviral Res. 2008. PMID: 18611413 Review.

6

Alpha-synuclein interacts with Glucocerebrosidase providing a molecular link between Parkinson and Gaucher diseases.

Yap TL, Gruschus JM, Velayati A, Westbroek W, Goldin E, Moaven N, Sidransky E, Lee JC. Yap TL, et al. J Biol Chem. 2011 Aug 12;286(32):28080-8. doi: 10.1074/jbc.M111.237859. Epub 2011 Jun 8. J Biol Chem. 2011. PMID: 21653695 Free PMC article.

7

Structural features of membrane-bound glucocerebrosidase and α-synuclein probed by neutron reflectometry and fluorescence spectroscopy.

Yap TL, Jiang Z, Heinrich F, Gruschus JM, Pfefferkorn CM, Barros M, Curtis JE, Sidransky E, Lee JC. Yap TL, et al. J Biol Chem. 2015 Jan 9;290(2):744-54. doi: 10.1074/jbc.M114.610584. Epub 2014 Nov 26. J Biol Chem. 2015. PMID: 25429104 Free PMC article.

8

α-Synuclein Shows High Affinity Interaction with Voltage-dependent Anion Channel, Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease.

Rostovtseva TK, Gurnev PA, Protchenko O, Hoogerheide DP, Yap TL, Philpott CC, Lee JC, Bezrukov SM. Rostovtseva TK, et al. Among authors: yap tl. J Biol Chem. 2015 Jul 24;290(30):18467-77. doi: 10.1074/jbc.M115.641746. Epub 2015 Jun 8. J Biol Chem. 2015. PMID: 26055708 Free PMC article.

9

Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity.

Yap TL, Velayati A, Sidransky E, Lee JC. Yap TL, et al. Mol Genet Metab. 2013 Jan;108(1):56-64. doi: 10.1016/j.ymgme.2012.11.010. Epub 2012 Nov 28. Mol Genet Metab. 2013. PMID: 23266198 Free PMC article.

10

Saposin C protects glucocerebrosidase against α-synuclein inhibition.

Yap TL, Gruschus JM, Velayati A, Sidransky E, Lee JC. Yap TL, et al. Biochemistry. 2013 Oct 15;52(41):7161-3. doi: 10.1021/bi401191v. Epub 2013 Oct 1. Biochemistry. 2013. PMID: 24070323 Free PMC article.

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