Earp JC - Search Results

1

Modeling corticosteroid effects in a rat model of rheumatoid arthritis II: mechanistic pharmacodynamic model for dexamethasone effects in Lewis rats with collagen-induced arthritis.

Earp JC, Dubois DC, Molano DS, Pyszczynski NA, Almon RR, Jusko WJ. Earp JC, et al. J Pharmacol Exp Ther. 2008 Aug;326(2):546-54. doi: 10.1124/jpet.108.137414. Epub 2008 Apr 30. J Pharmacol Exp Ther. 2008. PMID: 18448864 Free PMC article.

2

Assessment of drug interactions relevant to pharmacodynamic indirect response models.

Earp J, Krzyzanski W, Chakraborty A, Zamacona MK, Jusko WJ. Earp J, et al. J Pharmacokinet Pharmacodyn. 2004 Oct;31(5):345-80. doi: 10.1007/s10928-004-8319-4. J Pharmacokinet Pharmacodyn. 2004. PMID: 15669772

3

Synergism between arsenic trioxide and heat shock protein 90 inhibitors on signal transducer and activator of transcription protein 3 activity--pharmacodynamic drug-drug interaction modeling.

Wetzler M, Earp JC, Brady MT, Keng MK, Jusko WJ. Wetzler M, et al. Among authors: earp jc. Clin Cancer Res. 2007 Apr 1;13(7):2261-70. doi: 10.1158/1078-0432.CCR-06-2468. Clin Cancer Res. 2007. PMID: 17404111 Free PMC article.

4

Modeling corticosteroid effects in a rat model of rheumatoid arthritis I: mechanistic disease progression model for the time course of collagen-induced arthritis in Lewis rats.

Earp JC, Dubois DC, Molano DS, Pyszczynski NA, Keller CE, Almon RR, Jusko WJ. Earp JC, et al. J Pharmacol Exp Ther. 2008 Aug;326(2):532-45. doi: 10.1124/jpet.108.137372. Epub 2008 Apr 30. J Pharmacol Exp Ther. 2008. PMID: 18448865 Free PMC article.

5

Pharmacokinetics of dexamethasone in a rat model of rheumatoid arthritis.

Earp JC, Pyszczynski NA, Molano DS, Jusko WJ. Earp JC, et al. Biopharm Drug Dispos. 2008 Sep;29(6):366-72. doi: 10.1002/bdd.626. Biopharm Drug Dispos. 2008. PMID: 18613033 Free PMC article.

6

Quantitative dynamic models of arthritis progression in the rat.

Earp JC, Dubois DC, Almon RR, Jusko WJ. Earp JC, et al. Pharm Res. 2009 Jan;26(1):196-203. doi: 10.1007/s11095-008-9711-3. Epub 2008 Aug 30. Pharm Res. 2009. PMID: 18758921 Free PMC article.

7

Down-regulation of heat shock protein 70 improves arsenic trioxide and 17-DMAG effects on constitutive signal transducer and activator of transcription 3 activity.

Ghoshal S, Rao I, Earp JC, Jusko WJ, Wetzler M. Ghoshal S, et al. Among authors: earp jc. Cancer Chemother Pharmacol. 2010 Sep;66(4):681-9. doi: 10.1007/s00280-009-1210-7. Epub 2009 Dec 25. Cancer Chemother Pharmacol. 2010. PMID: 20035426 Free PMC article.

8

Modeling effects of dexamethasone on disease progression of bone mineral density in collagen-induced arthritic rats.

Lon HK, DuBois DC, Earp JC, Almon RR, Jusko WJ. Lon HK, et al. Among authors: earp jc. Pharmacol Res Perspect. 2015 Oct;3(5):e00169. doi: 10.1002/prp2.169. Epub 2015 Aug 3. Pharmacol Res Perspect. 2015. PMID: 26516581 Free PMC article.

9

Whole Body PBPK Modeling of Remdesivir and Its Metabolites to Aid in Estimating Active Metabolite Exposure in the Lung and Liver in Patients With Organ Dysfunction.

Fan J, Yang Y, Grimstein M, Zhang X, Kitabi E, Earp JC, Arya V, Reynolds KS, Zhu H, Wang Y. Fan J, et al. Among authors: earp jc. Clin Pharmacol Ther. 2022 Mar;111(3):624-634. doi: 10.1002/cpt.2445. Epub 2021 Nov 8. Clin Pharmacol Ther. 2022. PMID: 34656075

10

Utility of population pharmacokinetic modeling in the assessment of therapeutic protein-drug interactions.

Chow AT, Earp JC, Gupta M, Hanley W, Hu C, Wang DD, Zajic S, Zhu M; Population PK TPDI Working Group. Chow AT, et al. Among authors: earp jc. J Clin Pharmacol. 2014 May;54(5):593-601. doi: 10.1002/jcph.240. Epub 2013 Dec 6. J Clin Pharmacol. 2014. PMID: 24272952

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