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Aging-dependent reduction in glyoxalase 1 delays wound healing.
Fleming TH, Theilen TM, Masania J, Wunderle M, Karimi J, Vittas S, Bernauer R, Bierhaus A, Rabbani N, Thornalley PJ, Kroll J, Tyedmers J, Nawrotzki R, Herzig S, Brownlee M, Nawroth PP. Fleming TH, et al. Gerontology. 2013;59(5):427-37. doi: 10.1159/000351628. Epub 2013 Jun 22. Gerontology. 2013. PMID: 23797271
C. elegans as model for the study of high glucose- mediated life span reduction.
Schlotterer A, Kukudov G, Bozorgmehr F, Hutter H, Du X, Oikonomou D, Ibrahim Y, Pfisterer F, Rabbani N, Thornalley P, Sayed A, Fleming T, Humpert P, Schwenger V, Zeier M, Hamann A, Stern D, Brownlee M, Bierhaus A, Nawroth P, Morcos M. Schlotterer A, et al. Among authors: fleming t. Diabetes. 2009 Nov;58(11):2450-6. doi: 10.2337/db09-0567. Epub 2009 Aug 12. Diabetes. 2009. PMID: 19675139 Free PMC article.
Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy.
Bierhaus A, Fleming T, Stoyanov S, Leffler A, Babes A, Neacsu C, Sauer SK, Eberhardt M, Schnölzer M, Lasitschka F, Neuhuber WL, Kichko TI, Konrade I, Elvert R, Mier W, Pirags V, Lukic IK, Morcos M, Dehmer T, Rabbani N, Thornalley PJ, Edelstein D, Nau C, Forbes J, Humpert PM, Schwaninger M, Ziegler D, Stern DM, Cooper ME, Haberkorn U, Brownlee M, Reeh PW, Nawroth PP. Bierhaus A, et al. Among authors: fleming t. Nat Med. 2012 Jun;18(6):926-33. doi: 10.1038/nm.2750. Nat Med. 2012. PMID: 22581285
Methylglyoxal evokes pain by stimulating TRPA1.
Andersson DA, Gentry C, Light E, Vastani N, Vallortigara J, Bierhaus A, Fleming T, Bevan S. Andersson DA, et al. Among authors: fleming t. PLoS One. 2013 Oct 22;8(10):e77986. doi: 10.1371/journal.pone.0077986. eCollection 2013. PLoS One. 2013. PMID: 24167592 Free PMC article.
Methylglyoxal induces retinopathy-type lesions in the absence of hyperglycemia: studies in a rat model.
Schlotterer A, Kolibabka M, Lin J, Acunman K, Dietrich N, Sticht C, Fleming T, Nawroth P, Hammes HP. Schlotterer A, et al. Among authors: fleming t. FASEB J. 2019 Mar;33(3):4141-4153. doi: 10.1096/fj.201801146RR. Epub 2018 Nov 28. FASEB J. 2019. PMID: 30485119
-Schlotterer, A., Kolibabka, M., Lin, J., Acunman, K., Dietrich, N., Sticht, C., Fleming, T., Nawroth, P., Hammes, H.-P. Methylglyoxal induces retinopathy-type lesions in the absence of hyperglycemia: studies in a rat model....
-Schlotterer, A., Kolibabka, M., Lin, J., Acunman, K., Dietrich, N., Sticht, C., Fleming, T., Nawroth, P., Hammes, H.-P. Methy …
1,169 results