Palaninathan S - Search Results

1

A locking mechanism regulates RNA synthesis and host protein interaction by the hepatitis C virus polymerase.

Chinnaswamy S, Yarbrough I, Palaninathan S, Kumar CT, Vijayaraghavan V, Demeler B, Lemon SM, Sacchettini JC, Kao CC. Chinnaswamy S, et al. Among authors: palaninathan s. J Biol Chem. 2008 Jul 18;283(29):20535-46. doi: 10.1074/jbc.M801490200. Epub 2008 Apr 28. J Biol Chem. 2008. PMID: 18442978 Free PMC article.

2

Structural and functional analyses of the severe acute respiratory syndrome coronavirus endoribonuclease Nsp15.

Bhardwaj K, Palaninathan S, Alcantara JMO, Li Yi L, Guarino L, Sacchettini JC, Kao CC. Bhardwaj K, et al. Among authors: palaninathan s. J Biol Chem. 2008 Feb 8;283(6):3655-3664. doi: 10.1074/jbc.M708375200. Epub 2007 Nov 28. J Biol Chem. 2008. PMID: 18045871 Free PMC article.

3

High resolution crystal structures of Mycobacterium tuberculosis adenosine kinase: insights into the mechanism and specificity of this novel prokaryotic enzyme.

Reddy MCM, Palaninathan SK, Shetty ND, Owen JL, Watson MD, Sacchettini JC. Reddy MCM, et al. J Biol Chem. 2007 Sep 14;282(37):27334-27342. doi: 10.1074/jbc.M703290200. Epub 2007 Jun 26. J Biol Chem. 2007. PMID: 17597075 Free article.

4

Structural insights into the mechanism of the allosteric transitions of Mycobacterium tuberculosis cAMP receptor protein.

Reddy MCM, Palaninathan SK, Bruning JB, Thurman C, Smith D, Sacchettini JC. Reddy MCM, et al. Among authors: palaninathan sk. J Biol Chem. 2009 Dec 25;284(52):36581-36591. doi: 10.1074/jbc.M109.041343. Epub 2009 Sep 9. J Biol Chem. 2009. PMID: 19740754 Free PMC article.

5

Biochemical and genetic analyses of murine hepatitis virus Nsp15 endoribonuclease.

Kang H, Bhardwaj K, Li Y, Palaninathan S, Sacchettini J, Guarino L, Leibowitz JL, Kao CC. Kang H, et al. Among authors: palaninathan s. J Virol. 2007 Dec;81(24):13587-97. doi: 10.1128/JVI.00547-07. Epub 2007 Sep 26. J Virol. 2007. PMID: 17898055 Free PMC article.

6

Structural insight into pH-induced conformational changes within the native human transthyretin tetramer.

Palaninathan SK, Mohamedmohaideen NN, Snee WC, Kelly JW, Sacchettini JC. Palaninathan SK, et al. J Mol Biol. 2008 Oct 24;382(5):1157-67. doi: 10.1016/j.jmb.2008.07.029. Epub 2008 Jul 16. J Mol Biol. 2008. PMID: 18662699

7

Novel transthyretin amyloid fibril formation inhibitors: synthesis, biological evaluation, and X-ray structural analysis.

Palaninathan SK, Mohamedmohaideen NN, Orlandini E, Ortore G, Nencetti S, Lapucci A, Rossello A, Freundlich JS, Sacchettini JC. Palaninathan SK, et al. PLoS One. 2009 Jul 21;4(7):e6290. doi: 10.1371/journal.pone.0006290. PLoS One. 2009. PMID: 19621084 Free PMC article.

8

Crystal structures of the apo and ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein.

Shetty ND, Reddy MC, Palaninathan SK, Owen JL, Sacchettini JC. Shetty ND, et al. Among authors: palaninathan sk. Protein Sci. 2010 Aug;19(8):1513-24. doi: 10.1002/pro.430. Protein Sci. 2010. PMID: 20521335 Free PMC article.

9

Structure and function of the virulence-associated high-temperature requirement A of Mycobacterium tuberculosis.

Mohamedmohaideen NN, Palaninathan SK, Morin PM, Williams BJ, Braunstein M, Tichy SE, Locker J, Russell DH, Jacobs WR Jr, Sacchettini JC. Mohamedmohaideen NN, et al. Among authors: palaninathan sk. Biochemistry. 2008 Jun 10;47(23):6092-102. doi: 10.1021/bi701929m. Epub 2008 May 15. Biochemistry. 2008. PMID: 18479146

10

Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis.

Adamski-Werner SL, Palaninathan SK, Sacchettini JC, Kelly JW. Adamski-Werner SL, et al. J Med Chem. 2004 Jan 15;47(2):355-74. doi: 10.1021/jm030347n. J Med Chem. 2004. PMID: 14711308

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