Dobson CM - Search Results

1

Molecular determinants of the aggregation behavior of alpha- and beta-synuclein.

Rivers RC, Kumita JR, Tartaglia GG, Dedmon MM, Pawar A, Vendruscolo M, Dobson CM, Christodoulou J. Rivers RC, et al. Among authors: dobson cm. Protein Sci. 2008 May;17(5):887-98. doi: 10.1110/ps.073181508. Protein Sci. 2008. PMID: 18436957 Free PMC article.

2

Mapping long-range interactions in alpha-synuclein using spin-label NMR and ensemble molecular dynamics simulations.

Dedmon MM, Lindorff-Larsen K, Christodoulou J, Vendruscolo M, Dobson CM. Dedmon MM, et al. Among authors: dobson cm. J Am Chem Soc. 2005 Jan 19;127(2):476-7. doi: 10.1021/ja044834j. J Am Chem Soc. 2005. PMID: 15643843

3

Heat shock protein 70 inhibits alpha-synuclein fibril formation via preferential binding to prefibrillar species.

Dedmon MM, Christodoulou J, Wilson MR, Dobson CM. Dedmon MM, et al. Among authors: dobson cm. J Biol Chem. 2005 Apr 15;280(15):14733-40. doi: 10.1074/jbc.M413024200. Epub 2005 Jan 25. J Biol Chem. 2005. PMID: 15671022 Free article.

4

Prediction of "aggregation-prone" and "aggregation-susceptible" regions in proteins associated with neurodegenerative diseases.

Pawar AP, Dubay KF, Zurdo J, Chiti F, Vendruscolo M, Dobson CM. Pawar AP, et al. Among authors: dobson cm. J Mol Biol. 2005 Jul 8;350(2):379-92. doi: 10.1016/j.jmb.2005.04.016. J Mol Biol. 2005. PMID: 15925383

5

Similarities in the thermodynamics and kinetics of aggregation of disease-related Abeta(1-40) peptides.

Meinhardt J, Tartaglia GG, Pawar A, Christopeit T, Hortschansky P, Schroeckh V, Dobson CM, Vendruscolo M, Fändrich M. Meinhardt J, et al. Among authors: dobson cm. Protein Sci. 2007 Jun;16(6):1214-22. doi: 10.1110/ps.062734207. Protein Sci. 2007. PMID: 17525469 Free PMC article.

6

Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity.

Luheshi LM, Tartaglia GG, Brorsson AC, Pawar AP, Watson IE, Chiti F, Vendruscolo M, Lomas DA, Dobson CM, Crowther DC. Luheshi LM, et al. Among authors: dobson cm. PLoS Biol. 2007 Oct 30;5(11):e290. doi: 10.1371/journal.pbio.0050290. PLoS Biol. 2007. PMID: 17973577 Free PMC article.

7

Prediction of aggregation-prone regions in structured proteins.

Tartaglia GG, Pawar AP, Campioni S, Dobson CM, Chiti F, Vendruscolo M. Tartaglia GG, et al. Among authors: dobson cm. J Mol Biol. 2008 Jul 4;380(2):425-36. doi: 10.1016/j.jmb.2008.05.013. Epub 2008 May 13. J Mol Biol. 2008. PMID: 18514226

8

Mutational analysis of the aggregation-prone and disaggregation-prone regions of acylphosphatase.

Calamai M, Tartaglia GG, Vendruscolo M, Chiti F, Dobson CM. Calamai M, et al. Among authors: dobson cm. J Mol Biol. 2009 Apr 10;387(4):965-74. doi: 10.1016/j.jmb.2008.09.003. Epub 2008 Sep 12. J Mol Biol. 2009. PMID: 18809411

9

On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of alpha-synuclein with Congo red and lacmoid.

Lendel C, Bertoncini CW, Cremades N, Waudby CA, Vendruscolo M, Dobson CM, Schenk D, Christodoulou J, Toth G. Lendel C, et al. Among authors: dobson cm. Biochemistry. 2009 Sep 8;48(35):8322-34. doi: 10.1021/bi901285x. Biochemistry. 2009. PMID: 19645507

10

Determination of the free energy landscape of alpha-synuclein using spin label nuclear magnetic resonance measurements.

Allison JR, Varnai P, Dobson CM, Vendruscolo M. Allison JR, et al. Among authors: dobson cm. J Am Chem Soc. 2009 Dec 30;131(51):18314-26. doi: 10.1021/ja904716h. J Am Chem Soc. 2009. PMID: 20028147

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