Durrant D - Search Results

1

Mechanism of cell death induced by cis-3, 4', 5-trimethoxy-3'-aminostilbene in ovarian cancer.

Durrant D, Richards JE, Walker WT, Baker KA, Simoni D, Lee RM. Durrant D, et al. Gynecol Oncol. 2008 Jul;110(1):110-7. doi: 10.1016/j.ygyno.2008.02.031. Epub 2008 Apr 22. Gynecol Oncol. 2008. PMID: 18433847

2

Development of water soluble derivatives of cis-3, 4', 5-trimethoxy-3'-aminostilbene for optimization and use in cancer therapy.

Durrant DE, Richards J, Tripathi A, Kellogg GE, Marchetti P, Eleopra M, Grisolia G, Simoni D, Lee RM. Durrant DE, et al. Invest New Drugs. 2009 Feb;27(1):41-52. doi: 10.1007/s10637-008-9139-y. Epub 2008 May 31. Invest New Drugs. 2009. PMID: 18516499

3

cis-3, 4', 5-Trimethoxy-3'-aminostilbene disrupts tumor vascular perfusion without damaging normal organ perfusion.

Durrant D, Corwin F, Simoni D, Zhao M, Rudek MA, Salloum FN, Kukreja RC, Fatouros PP, Lee RM. Durrant D, et al. Cancer Chemother Pharmacol. 2009 Jan;63(2):191-200. doi: 10.1007/s00280-008-0726-6. Epub 2008 Mar 26. Cancer Chemother Pharmacol. 2009. PMID: 18365199

4

Stilbene 5c, a microtubule poison with vascular disrupting properties that induces multiple modes of growth arrest and cell death.

Alotaibi MR, Asnake B, Di X, Beckman MJ, Durrant D, Simoni D, Baruchello R, Lee RM, Schwartz EL, Gewirtz DA. Alotaibi MR, et al. Among authors: durrant d. Biochem Pharmacol. 2013 Dec 15;86(12):1688-98. doi: 10.1016/j.bcp.2013.10.007. Epub 2013 Oct 19. Biochem Pharmacol. 2013. PMID: 24144631 Free PMC article.

5

Stilbene derivatives that are colchicine-site microtubule inhibitors have antileukemic activity and minimal systemic toxicity.

Cao TM, Durrant D, Tripathi A, Liu J, Tsai S, Kellogg GE, Simoni D, Lee RM. Cao TM, et al. Among authors: durrant d. Am J Hematol. 2008 May;83(5):390-7. doi: 10.1002/ajh.21104. Am J Hematol. 2008. PMID: 18175355 Free article.

6

Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity.

Tripathi A, Durrant D, Lee RM, Baruchello R, Romagnoli R, Simoni D, Kellogg GE. Tripathi A, et al. Among authors: durrant d. J Enzyme Inhib Med Chem. 2009 Dec;24(6):1237-44. doi: 10.3109/14756360902787055. J Enzyme Inhib Med Chem. 2009. PMID: 19912057 Free PMC article.

7

The bortezomib-induced mitochondrial damage is mediated by accumulation of active protein kinase C-delta.

Durrant D, Liu J, Yang HS, Lee RM. Durrant D, et al. Biochem Biophys Res Commun. 2004 Sep 3;321(4):905-8. doi: 10.1016/j.bbrc.2004.07.049. Biochem Biophys Res Commun. 2004. PMID: 15358112

8

Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction.

Das A, Durrant D, Mitchell C, Mayton E, Hoke NN, Salloum FN, Park MA, Qureshi I, Lee R, Dent P, Kukreja RC. Das A, et al. Among authors: durrant d. Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18202-7. doi: 10.1073/pnas.1006965107. Epub 2010 Sep 30. Proc Natl Acad Sci U S A. 2010. PMID: 20884855 Free PMC article.

9

Development of hemiasterlin derivatives as potential anticancer agents that inhibit tubulin polymerization and synergize with a stilbene tubulin inhibitor.

Hsu LC, Durrant DE, Huang CC, Chi NW, Baruchello R, Rondanin R, Rullo C, Marchetti P, Grisolia G, Simoni D, Lee RM. Hsu LC, et al. Among authors: durrant de. Invest New Drugs. 2012 Aug;30(4):1379-88. doi: 10.1007/s10637-011-9702-9. Epub 2011 Jun 8. Invest New Drugs. 2012. PMID: 21655917

10

N-benzyladriamycin-14-valerate (AD198) induces apoptosis through protein kinase C-delta-induced phosphorylation of phospholipid scramblase 3.

He Y, Liu J, Durrant D, Yang HS, Sweatman T, Lothstein L, Lee RM. He Y, et al. Among authors: durrant d. Cancer Res. 2005 Nov 1;65(21):10016-23. doi: 10.1158/0008-5472.CAN-05-1688. Cancer Res. 2005. PMID: 16267027

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