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Intralesional TLR4 agonist treatment strengthens the organ defense against colonizing cancer cells in the brain.
Blazquez R, Chuang HN, Wenske B, Trigueros L, Wlochowitz D, Liguori R, Ferrazzi F, Regen T, Proescholdt MA, Rohde V, Riemenschneider MJ, Stadelmann C, Bleckmann A, Beißbarth T, van Rossum D, Hanisch UK, Pukrop T. Blazquez R, et al. Among authors: hanisch uk. Oncogene. 2022 Nov;41(46):5008-5019. doi: 10.1038/s41388-022-02496-3. Epub 2022 Oct 12. Oncogene. 2022. PMID: 36224342 Free PMC article.
LEF1 supports metastatic brain colonization by regulating glutathione metabolism and increasing ROS resistance in breast cancer.
Blazquez R, Rietkötter E, Wenske B, Wlochowitz D, Sparrer D, Vollmer E, Müller G, Seegerer J, Sun X, Dettmer K, Barrantes-Freer A, Stange L, Utpatel K, Bleckmann A, Treiber H, Bohnenberger H, Lenz C, Schulz M, Reimelt C, Hackl C, Grade M, Büyüktas D, Siam L, Balkenhol M, Stadelmann C, Kube D, Krahn MP, Proescholdt MA, Riemenschneider MJ, Evert M, Oefner PJ, Klein CA, Hanisch UK, Binder C, Pukrop T. Blazquez R, et al. Among authors: hanisch uk. Int J Cancer. 2020 Jun 1;146(11):3170-3183. doi: 10.1002/ijc.32742. Epub 2019 Nov 11. Int J Cancer. 2020. PMID: 31626715
Microglial phenotype: is the commitment reversible?
Schwartz M, Butovsky O, Brück W, Hanisch UK. Schwartz M, et al. Among authors: hanisch uk. Trends Neurosci. 2006 Feb;29(2):68-74. doi: 10.1016/j.tins.2005.12.005. Epub 2006 Jan 6. Trends Neurosci. 2006. PMID: 16406093 Review.
Fibronectin is elevated in the cerebrospinal fluid of patients suffering from bacterial meningitis and enhances inflammation caused by bacterial products in primary mouse microglial cell cultures.
Goos M, Lange P, Hanisch UK, Prinz M, Scheffel J, Bergmann R, Ebert S, Nau R. Goos M, et al. Among authors: hanisch uk. J Neurochem. 2007 Sep;102(6):2049-2060. doi: 10.1111/j.1471-4159.2007.04683.x. Epub 2007 Jun 11. J Neurochem. 2007. PMID: 17561936 Free article.
116 results