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Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylation.
Stolovich M, Tang H, Hornstein E, Levy G, Cohen R, Bae SS, Birnbaum MJ, Meyuhas O. Stolovich M, et al. Among authors: bae ss. Mol Cell Biol. 2002 Dec;22(23):8101-13. doi: 10.1128/MCB.22.23.8101-8113.2002. Mol Cell Biol. 2002. PMID: 12417714 Free PMC article.
Molecular and genetic studies imply Akt-mediated signaling promotes protein kinase CbetaII alternative splicing via phosphorylation of serine/arginine-rich splicing factor SRp40.
Patel NA, Kaneko S, Apostolatos HS, Bae SS, Watson JE, Davidowitz K, Chappell DS, Birnbaum MJ, Cheng JQ, Cooper DR. Patel NA, et al. Among authors: bae ss. J Biol Chem. 2005 Apr 8;280(14):14302-9. doi: 10.1074/jbc.M411485200. Epub 2005 Jan 31. J Biol Chem. 2005. PMID: 15684423 Free article.
245 results