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Species differences in the pharmacokinetics of KW-7158 [(2S)-(+)-3,3,3-Trifluoro-2-hydroxy-2-methyl-N-(5,5,10-trioxo-4,10-dihydrothieno[3,2-c][1]benzothiepin-9-yl)propanamide]: formation of hydrolyzed metabolite in human and animals.
Maeda H, Kodaira H, Fujita K, Kobayashi H, Ushiki J, Nakanishi T, Tamai I. Maeda H, et al. Among authors: kodaira h. Xenobiotica. 2012 Jul;42(7):649-59. doi: 10.3109/00498254.2011.652993. Epub 2012 Feb 10. Xenobiotica. 2012. PMID: 22324379
An Asian variant of intravascular lymphoma diagnosed through splenectomy.
Yoshikawa S, Kobayashi H, Kanda S, Furihata K, Ueno M, Kaneki T, Kodaira H, Ichikawa N, Koyama S, Saito H. Yoshikawa S, et al. Among authors: kodaira h. Intern Med. 2002 Dec;41(12):1215-6. doi: 10.2169/internalmedicine.41.1215. Intern Med. 2002. PMID: 12521220 Free article. No abstract available.
Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as a surrogate.
Kodaira H, Kusuhara H, Fujita T, Ushiki J, Fuse E, Sugiyama Y. Kodaira H, et al. J Pharmacol Exp Ther. 2011 Dec;339(3):935-44. doi: 10.1124/jpet.111.180398. Epub 2011 Sep 20. J Pharmacol Exp Ther. 2011. PMID: 21934030
Development of a novel class of peroxisome proliferator-activated receptor (PPAR) gamma ligands as an anticancer agent with a unique binding mode based on a non-thiazolidinedione scaffold.
Yamamoto K, Tamura T, Nakamura R, Hosoe S, Matsubara M, Nagata K, Kodaira H, Uemori T, Takahashi Y, Suzuki M, Saito JI, Ueno K, Shuto S. Yamamoto K, et al. Among authors: kodaira h. Bioorg Med Chem. 2019 Nov 15;27(22):115122. doi: 10.1016/j.bmc.2019.115122. Epub 2019 Sep 16. Bioorg Med Chem. 2019. PMID: 31623970 Free article.
91 results