Van Lanen SG - Search Results

1

Biosynthesis of enediyne antitumor antibiotics.

Van Lanen SG, Shen B. Van Lanen SG, et al. Curr Top Med Chem. 2008;8(6):448-59. doi: 10.2174/156802608783955656. Curr Top Med Chem. 2008. PMID: 18397168 Free PMC article. Review.

2

Antitumor antibiotics: bleomycin, enediynes, and mitomycin.

Galm U, Hager MH, Van Lanen SG, Ju J, Thorson JS, Shen B. Galm U, et al. Among authors: van lanen sg. Chem Rev. 2005 Feb;105(2):739-58. doi: 10.1021/cr030117g. Chem Rev. 2005. PMID: 15700963 No abstract available.

3

The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases.

Liu W, Nonaka K, Nie L, Zhang J, Christenson SD, Bae J, Van Lanen SG, Zazopoulos E, Farnet CM, Yang CF, Shen B. Liu W, et al. Among authors: van lanen sg. Chem Biol. 2005 Mar;12(3):293-302. doi: 10.1016/j.chembiol.2004.12.013. Chem Biol. 2005. PMID: 15797213

4

Biosynthesis of the beta-amino acid moiety of the enediyne antitumor antibiotic C-1027 featuring beta-amino acyl-S-carrier protein intermediates.

Van Lanen SG, Dorrestein PC, Christenson SD, Liu W, Ju J, Kelleher NL, Shen B. Van Lanen SG, et al. J Am Chem Soc. 2005 Aug 24;127(33):11594-5. doi: 10.1021/ja052871k. J Am Chem Soc. 2005. PMID: 16104723

5

Microbial genomics for the improvement of natural product discovery.

Van Lanen SG, Shen B. Van Lanen SG, et al. Curr Opin Microbiol. 2006 Jun;9(3):252-60. doi: 10.1016/j.mib.2006.04.002. Epub 2006 May 2. Curr Opin Microbiol. 2006. PMID: 16651020 Review.

6

Substrate specificity of the adenylation enzyme SgcC1 involved in the biosynthesis of the enediyne antitumor antibiotic C-1027.

Van Lanen SG, Lin S, Dorrestein PC, Kelleher NL, Shen B. Van Lanen SG, et al. J Biol Chem. 2006 Oct 6;281(40):29633-40. doi: 10.1074/jbc.M605887200. Epub 2006 Aug 3. J Biol Chem. 2006. PMID: 16887797 Free article.

7

The bifunctional glyceryl transferase/phosphatase OzmB belonging to the HAD superfamily that diverts 1,3-bisphosphoglycerate into polyketide biosynthesis.

Dorrestein PC, Van Lanen SG, Li W, Zhao C, Deng Z, Shen B, Kelleher NL. Dorrestein PC, et al. Among authors: van lanen sg. J Am Chem Soc. 2006 Aug 16;128(32):10386-7. doi: 10.1021/ja0639362. J Am Chem Soc. 2006. PMID: 16895402

8

The structure of L-tyrosine 2,3-aminomutase from the C-1027 enediyne antitumor antibiotic biosynthetic pathway.

Christianson CV, Montavon TJ, Van Lanen SG, Shen B, Bruner SD. Christianson CV, et al. Among authors: van lanen sg. Biochemistry. 2007 Jun 19;46(24):7205-14. doi: 10.1021/bi7003685. Epub 2007 May 22. Biochemistry. 2007. PMID: 17516659

9

Characterization of NcsB2 as a promiscuous naphthoic acid/coenzyme A ligase integral to the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin.

Cooke HA, Zhang J, Griffin MA, Nonaka K, Van Lanen SG, Shen B, Bruner SD. Cooke HA, et al. Among authors: van lanen sg. J Am Chem Soc. 2007 Jun 27;129(25):7728-9. doi: 10.1021/ja071886a. Epub 2007 Jun 1. J Am Chem Soc. 2007. PMID: 17539640 No abstract available.

10

Regiospecific chlorination of (S)-beta-tyrosyl-S-carrier protein catalyzed by SgcC3 in the biosynthesis of the enediyne antitumor antibiotic C-1027.

Lin S, Van Lanen SG, Shen B. Lin S, et al. Among authors: van lanen sg. J Am Chem Soc. 2007 Oct 17;129(41):12432-8. doi: 10.1021/ja072311g. Epub 2007 Sep 22. J Am Chem Soc. 2007. PMID: 17887753 Free PMC article.

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