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Page 1
Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase.
Kirkland TA, Adler M, Bauman JG, Chen M, Haeggström JZ, King B, Kochanny MJ, Liang AM, Mendoza L, Phillips GB, Thunnissen M, Trinh L, Whitlow M, Ye B, Ye H, Parkinson J, Guilford WJ. Kirkland TA, et al. Bioorg Med Chem. 2008 May 1;16(9):4963-83. doi: 10.1016/j.bmc.2008.03.042. Epub 2008 Mar 20. Bioorg Med Chem. 2008. PMID: 18394906
Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A4 hydrolase.
Ye B, Bauman J, Chen M, Davey D, Khim SK, King B, Kirkland T, Kochanny M, Liang A, Lentz D, May K, Mendoza L, Phillips G, Selchau V, Schlyer S, Tseng JL, Wei RG, Ye H, Parkinson J, Guilford WJ. Ye B, et al. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3891-4. doi: 10.1016/j.bmcl.2008.06.046. Epub 2008 Jun 18. Bioorg Med Chem Lett. 2008. PMID: 18586492
Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors.
Khim SK, Bauman J, Evans J, Freeman B, King B, Kirkland T, Kochanny M, Lentz D, Liang A, Mendoza L, Phillips G, Tseng JL, Wei RG, Ye H, Yu L, Parkinson J, Guilford WJ. Khim SK, et al. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3895-8. doi: 10.1016/j.bmcl.2008.06.041. Epub 2008 Jun 18. Bioorg Med Chem Lett. 2008. PMID: 18590959
Homogeneous Assay for Target Engagement Utilizing Bioluminescent Thermal Shift.
Dart ML, Machleidt T, Jost E, Schwinn MK, Robers MB, Shi C, Kirkland TA, Killoran MP, Wilkinson JM, Hartnett JR, Zimmerman K, Wood KV. Dart ML, et al. Among authors: kirkland ta. ACS Med Chem Lett. 2018 Apr 16;9(6):546-551. doi: 10.1021/acsmedchemlett.8b00081. eCollection 2018 Jun 14. ACS Med Chem Lett. 2018. PMID: 29937980 Free PMC article.
Total synthesis of (+)-ambruticin S.
Kirkland TA, Colucci J, Geraci LS, Marx MA, Schneider M, Kaelin DE Jr, Martin SF. Kirkland TA, et al. J Am Chem Soc. 2001 Dec 12;123(49):12432-3. doi: 10.1021/ja011867f. J Am Chem Soc. 2001. PMID: 11734054 No abstract available.
NanoBRET--A Novel BRET Platform for the Analysis of Protein-Protein Interactions.
Machleidt T, Woodroofe CC, Schwinn MK, Méndez J, Robers MB, Zimmerman K, Otto P, Daniels DL, Kirkland TA, Wood KV. Machleidt T, et al. Among authors: kirkland ta. ACS Chem Biol. 2015 Aug 21;10(8):1797-804. doi: 10.1021/acschembio.5b00143. Epub 2015 Jun 9. ACS Chem Biol. 2015. PMID: 26006698 Free article.
42 results