Carroll JB - Search Results

1

Cortical thickness measured from MRI in the YAC128 mouse model of Huntington's disease.

Lerch JP, Carroll JB, Dorr A, Spring S, Evans AC, Hayden MR, Sled JG, Henkelman RM. Lerch JP, et al. Among authors: carroll jb. Neuroimage. 2008 Jun;41(2):243-51. doi: 10.1016/j.neuroimage.2008.02.019. Epub 2008 Feb 26. Neuroimage. 2008. PMID: 18387826

2

Automated deformation analysis in the YAC128 Huntington disease mouse model.

Lerch JP, Carroll JB, Spring S, Bertram LN, Schwab C, Hayden MR, Henkelman RM. Lerch JP, et al. Among authors: carroll jb. Neuroimage. 2008 Jan 1;39(1):32-9. doi: 10.1016/j.neuroimage.2007.08.033. Epub 2007 Aug 31. Neuroimage. 2008. PMID: 17942324

3

Natural history of disease in the YAC128 mouse reveals a discrete signature of pathology in Huntington disease.

Carroll JB, Lerch JP, Franciosi S, Spreeuw A, Bissada N, Henkelman RM, Hayden MR. Carroll JB, et al. Neurobiol Dis. 2011 Jul;43(1):257-65. doi: 10.1016/j.nbd.2011.03.018. Epub 2011 Mar 31. Neurobiol Dis. 2011. PMID: 21458571

4

Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease.

Carroll JB, Southwell AL, Graham RK, Lerch JP, Ehrnhoefer DE, Cao LP, Zhang WN, Deng Y, Bissada N, Henkelman RM, Hayden MR. Carroll JB, et al. Mol Neurodegener. 2011 Aug 19;6:59. doi: 10.1186/1750-1326-6-59. Mol Neurodegener. 2011. PMID: 21854568 Free PMC article.

5

Phenotypic abnormalities in the YAC128 mouse model of Huntington disease are penetrant on multiple genetic backgrounds and modulated by strain.

Van Raamsdonk JM, Metzler M, Slow E, Pearson J, Schwab C, Carroll J, Graham RK, Leavitt BR, Hayden MR. Van Raamsdonk JM, et al. Neurobiol Dis. 2007 Apr;26(1):189-200. doi: 10.1016/j.nbd.2006.12.010. Epub 2006 Dec 29. Neurobiol Dis. 2007. PMID: 17276692

6

Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease.

Joshi PR, Wu NP, André VM, Cummings DM, Cepeda C, Joyce JA, Carroll JB, Leavitt BR, Hayden MR, Levine MS, Bamford NS. Joshi PR, et al. Among authors: carroll jb. J Neurosci. 2009 Feb 25;29(8):2414-27. doi: 10.1523/JNEUROSCI.5687-08.2009. J Neurosci. 2009. PMID: 19244517 Free PMC article.

7

A fully humanized transgenic mouse model of Huntington disease.

Southwell AL, Warby SC, Carroll JB, Doty CN, Skotte NH, Zhang W, Villanueva EB, Kovalik V, Xie Y, Pouladi MA, Collins JA, Yang XW, Franciosi S, Hayden MR. Southwell AL, et al. Among authors: carroll jb. Hum Mol Genet. 2013 Jan 1;22(1):18-34. doi: 10.1093/hmg/dds397. Epub 2012 Sep 21. Hum Mol Genet. 2013. PMID: 23001568 Free PMC article.

8

Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation.

Valenza M, Carroll JB, Leoni V, Bertram LN, Björkhem I, Singaraja RR, Di Donato S, Lutjohann D, Hayden MR, Cattaneo E. Valenza M, et al. Among authors: carroll jb. Hum Mol Genet. 2007 Sep 15;16(18):2187-98. doi: 10.1093/hmg/ddm170. Epub 2007 Jul 5. Hum Mol Genet. 2007. PMID: 17613541

9

Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene / allele-specific silencing of mutant huntingtin.

Carroll JB, Warby SC, Southwell AL, Doty CN, Greenlee S, Skotte N, Hung G, Bennett CF, Freier SM, Hayden MR. Carroll JB, et al. Mol Ther. 2011 Dec;19(12):2178-85. doi: 10.1038/mt.2011.201. Epub 2011 Oct 4. Mol Ther. 2011. PMID: 21971427 Free PMC article.

10

In vivo evaluation of candidate allele-specific mutant huntingtin gene silencing antisense oligonucleotides.

Southwell AL, Skotte NH, Kordasiewicz HB, Østergaard ME, Watt AT, Carroll JB, Doty CN, Villanueva EB, Petoukhov E, Vaid K, Xie Y, Freier SM, Swayze EE, Seth PP, Bennett CF, Hayden MR. Southwell AL, et al. Among authors: carroll jb. Mol Ther. 2014 Dec;22(12):2093-2106. doi: 10.1038/mt.2014.153. Epub 2014 Aug 7. Mol Ther. 2014. PMID: 25101598 Free PMC article.

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